MeSH tree: D02.355.726.305
Researchers have found that mitochondrial dysfunction in the blood-brain barrier (BBB) may lead to neuropsychiatric disease in some patients with DiGeorge syndrome.
Aug 20, 2025
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The lab of The Wistar Institute's Jessie Villanueva, Ph.D., has identified a new strategy for attacking treatment-resistant melanoma: inhibiting the gene S6K2. The team has published their findings in a paper titled "Selective ...
Feb 5, 2025
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30
Osteoarthritis (OA) represents the most prevalent form of chronic degenerative joint disease worldwide. The dynamic interplay between cartilage and subchondral bone is essential for preserving joint structural and functional ...
Jun 28, 2024
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The LENS trial has demonstrated that fenofibrate, a drug usually used to lower cholesterol, reduces the risk of progression of diabetic retinopathy by 27%. The results were announced at the American Diabetes Association Scientific ...
Jun 24, 2024
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Wistar researchers successfully tested a simple intervention that could unlock greater anti-tumor power in therapies that use T cells—an approach known as "cell-based therapy," which uses specially designed T cells to fight ...
Dec 13, 2023
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Degeneration of myelin, an insulating sheath required for rapid communication between nerve cells, and neuroinflammation are notable hallmarks of Multiple Sclerosis (MS) and related neurodegenerative disorders such as Alzheimer's ...
Apr 20, 2023
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The FDA-approved, lipid-lowering medication gemfibrozil may prevent the progression of juvenile Batten disease, according to researchers at RUSH. Results from the study were recently published in The Journal of Neuroscience.
Mar 17, 2023
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After showing promise in early laboratory research, the cholesterol-lowering drug fenofibrate had no significant effect on COVID-19 outcomes in a multicenter international randomized clinical trial led by Penn Medicine scientists. ...
Nov 7, 2022
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Regular treadmill exercise helped improve Parkinson's disease symptoms in mice in a recent study by researchers at RUSH University Medical Center. The results of the study were recently published in the Cell Reports.
Aug 18, 2022
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