Targeting ABC transporters in pancreatic ductal carcinoma—past, present, or future?
A new editorial paper titled "Targeting ABC transporters in PDAC—past, present, or future?" has been published in Oncotarget.
Jul 10, 2024
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Organic Chemicals: News and Research on Cyclodecanes
MeSH tree: D02.455.426.392.368.242
Tool predicts nerve damage from breast cancer treatment
Many women treated for breast cancer using taxanes, a type of cytostatic drug, often experience side effects in the nervous system. Researchers at Linköping University have developed a tool that can predict the risk level ...
Jul 9, 2024
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Researchers complete first trial of Black patients with early-stage breast cancer
Black patients with early-stage breast cancer who were treated with docetaxel chemotherapy every 3 weeks had less drug-induced peripheral neuropathy and significantly fewer dose reductions compared to those who received weekly ...
Jun 4, 2024
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Improving the safety of iPS cell-derived pancreatic islets by eliminating unwanted cells
A team of researchers has uncovered the identity of off-target cells responsible for abnormal outgrowth and devised a method to eliminate them from iPS cell-derived pancreatic tissues in development for cell therapy against ...
May 13, 2024
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Amgen plows ahead with costly, highly toxic cancer dosing despite FDA challenge
When doctors began using the drug sotorasib in 2021 with high expectations for its innovative approach to attacking lung cancer, retired medical technician Don Crosslin was an early beneficiary. Crosslin started the drug ...
May 9, 2024
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Adding chemotherapy to hormone therapy helps control locally advanced prostate cancer, finds study
For patients with locally advanced prostate cancer, combined treatment with chemotherapy and hormonal therapy offers extended control of prostate-specific antigen (PSA) levels, compared to hormonal therapy alone, according ...
Apr 17, 2024
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Combining causal and correlative approaches to discover response biomarkers to paclitaxel
A new research perspective titled "Combining causal and correlative approaches to discover biomarkers of response to paclitaxel" has been published in Oncotarget.
Feb 21, 2024
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New therapeutic strategy for metastatic prostate cancer patients resistant to standard treatment
A team of researchers from the Badalona Applied Research Group in Oncology (B·ARGO) and the Urologic Tumors Unit of the Institut Català d'Oncologia (ICO) and the Germans Trias i Pujol Research Institute (IGTP) have found ...
Feb 2, 2024
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Protein discovery could help solve prostate cancer drug resistance
Researchers have identified a receptor protein known as CHRM1 as a key player in prostate cancer cells' resistance to docetaxel, a commonly-used chemotherapy drug to treat advanced cancer that has spread beyond the prostate.
Jan 22, 2024
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A novel approach for lymph node metastasis treatment
Researchers at Tohoku University have discovered a new approach for treating lymph node metastasis. Anticancer drugs are administered directly into the LNs under ultrasound guidance (lymphatic drug delivery system or LDDS) ...
Jan 12, 2024
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