MeSH tree: D02.626.300
Most breast cancers are worsened by estrogens. To combat the recurrence of these cancers, clinicians treat patients with inhibitors for estrogen production, like letrozole. But many patients do not adhere to this treatment ...
Jun 8, 2026
0
4
Late-breaking results from the Phase III NRG GY019 trial indicate that letrozole monotherapy (L) did not demonstrate noninferiority to paclitaxel/carboplatin followed by letrozole (PC/L) for progression-free survival (PFS) ...
Apr 13, 2026
0
3
A drug mimicking the hormone progesterone has anti-cancer activity when used together with conventional anti-estrogen treatment for women with breast cancer, a new Cambridge-led trial has found.
Jan 5, 2026
0
33
Scientists at UC San Francisco and Gladstone Institutes have identified cancer drugs that promise to reverse the changes that occur in the brain during Alzheimer's, potentially slowing or even reversing its symptoms.
Jul 21, 2025
0
240
Retrospective analyses of epidemiologic data have repeatedly shown that COVID-19 mortality is higher in males compared to females. However, the underlying factors mediating sex-specific disease outcome were largely unknown.
Aug 14, 2023
0
39
The GOG Foundation, Inc. (GOG) announced positive results from an investigator-initiated phase II trial, sponsored by the GOG, investigating the combination of ribociclib and letrozole in patients with recurrent low-grade ...
Mar 27, 2023
0
44
In a study using a first-of-its kind mouse model of aging that mimics breast cancer development in estrogen receptor-positive post-menopausal women, investigators at Georgetown Lombardi Comprehensive Cancer Center and colleagues ...
Dec 1, 2022
0
34
A gene expression-based screening assay using chimeric mice with humanized hepatocytes revealed that letrozole has a modifying effect on fibrosis-related gene expression in the hepatocytes, including YAP, CTGF, TGF-β, and ...
Nov 8, 2022
1
66
