Expanding essential wound care for people who use drugs
A study published in the Harm Reduction Journal identifies critical factors and strategies for expanding low-barrier wound care services for people who use drugs (PWUD).
Jun 18, 2025
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Organic Chemicals: News and Research on Xylazine
MeSH tree: D02.886.665.985
Medetomidine: What you need to know about the animal sedative turning up in opioid deaths
The opioid crisis, increasingly driven by synthetic opioids, continues to claim tens of thousands of lives annually in the US alone. Similar crises have arisen all over the western world.
May 13, 2025
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Animal sedative medetomidine is showing up in the US illegal drug supply, CDC says
The animal sedative medetomidine is increasingly showing up in the U.S. illegal drug supply, according to three reports released Thursday.
May 2, 2025
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New protocols for treating patients with xylazine wounds
A multi-disciplinary team of UPMC clinicians has developed comprehensive clinical protocols for managing hospitalized patients exposed to xylazine—a veterinary sedative increasingly found in the unregulated opioid supply. ...
Apr 17, 2025
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Animal tranquilizers found in illegal opioids may suppress the lifesaving medication naloxone
The animal tranquilizers xylazine and medetomidine are in approximately one-third of the illegal opioids available in the U.S., including fentanyl, heroin and oxycodone. Animal tranquilizers enhance the user's euphoric high ...
Apr 7, 2025
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Medetomidine is replacing xylazine in Philly street fentanyl, creating new hurdles for health care providers
Philadelphia's street opioid supply—or "dope" market—is constantly changing. As health care workers and researchers who care for people who use drugs in our community, we have witnessed these shifts firsthand.
Mar 26, 2025
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Xylazine detected in US–Mexico border drug supply, study finds
Researchers at the University of California San Diego School of Medicine, in collaboration with the Prevencasa free clinic in Tijuana, Mexico, have confirmed the presence of xylazine in the illicit drug supply at the U.S.–Mexico ...
Mar 20, 2025
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Fewer deaths, new substances and evolving treatments in Philly's opioid epidemic: Four essential reads
In Philadelphia, fatal overdoses are the No. 3 cause of death after heart disease and cancer. That's been the case each year since 2016, except in 2020 and 2021 when COVID-19 deaths outpaced overdose deaths. The vast majority ...
Mar 17, 2025
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Philly's street fentanyl contains an industrial chemical called BTMPS that's an ingredient in plastic
As much as half of the fentanyl sold on Philly's streets contains an industrial chemical used in plastics manufacturing. That's according to our November 2024 testing of fentanyl samples collected in Philadelphia's Kensington ...
Mar 6, 2025
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Surgeons detail challenges in treating 'tranq' wounds amid Philadelphia's Xylazine crisis
A new study examining the treatment of xylazine-associated wounds in Philadelphia sheds light on the severe medical complications and health care challenges caused by the widespread presence of the drug in the city's illicit ...
Feb 17, 2025
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