MeSH tree: C23.550.210
A new study finds that when p53, one of the most important cancer-protecting genes, stops working, cells produce too much RNA and consume excessive amounts of the building blocks needed to copy their DNA. This shortage disrupts ...
Sep 7, 2026
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Researchers have solved a long-standing mystery of how abnormal chromosomes drive cancer, identifying 81 new genes involved in aggressive breast cancer. The discovery expands understanding of the cellular processes behind ...
Jul 8, 2026
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A comprehensive multi-cancer study by researchers at The University of Texas MD Anderson Cancer Center has revealed that cancer cells within tumors are genetically diverse, yet all carry the same core genetic changes that ...
Jun 16, 2026
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Chromosomal instability is a common feature in many solid tumors and is associated with greater aggressiveness. For years, its main contribution to cancer was thought to be driving the evolution of tumor genomes, causing ...
Jun 6, 2026
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Researchers at Trinity have found that a largely overlooked form of cancer evolution, which drives aggressive disease and poor patient outcomes, is far more widespread than previously thought. Comparing chromosome patterns ...
Jun 2, 2026
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Megan Sweet slices tumors. A normal day in the lab finds the Virginia Tech graduate student with hands deep inside a refrigerated metal box, pulling a mounted mouse-grown tumor incrementally closer to a razor-sharp blade. ...
May 25, 2026
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A study by researchers at the University of Birmingham has identified a new biomarker for response to a specific cancer therapy, treating children with Ewing Sarcoma and other tumor types. The study, which is a Phase I/II ...
May 22, 2026
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A new study led by NYU Langone Health researchers has found that cancer cells are better able to resist treatments when they have an abnormal number of chromosomes, the DNA strands wound up in bundles that control which genetic ...
May 7, 2026
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Researchers at Tulane University School of Medicine have discovered that if animal cells gain an extra set of chromosomes, a condition known as polyploidy, they activate a stress signaling pathway that causes them to become ...
Apr 21, 2026
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Scientists have taken an important step toward a gene therapy that could one day turn off the extra genetic material that causes Down syndrome (DS). Down syndrome is a genetic condition caused by an extra chromosome 21 (and ...
