MeSH tree: C23.550.737
There is no treatment available today to stop the death of brain cells in neurodegenerative diseases known as tauopathies, including Alzheimer's disease, in which twisted clumps of a protein called tau accumulate in the brain.
Sep 28, 2026
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Immune cells that normally protect the body from damage by attacking foreign or infected cells are found in the brains of patients with Alzheimer's disease and related disorders at much higher levels than in healthy brains. ...
Sep 3, 2026
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An analysis of the brain of a deceased Alzheimer's disease (AD) clinical trial participant found that regions where an anti-amyloid therapy successfully cleared amyloid plaques showed little to no evidence of tau tangles, ...
Jul 14, 2026
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142
A new study identified protein targets and drug candidates, including opportunities to repurpose existing drugs. Six key proteins were highlighted as potentially providing new insights and supporting future treatment development ...
Jun 10, 2026
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17
New research from the University of Adelaide has explored the genomic links within the index used to measure healthy aging—intrinsic capacity (IC), paving the way for potential targeted interventions.
Oct 10, 2025
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25
One fundamental feature of neurodegenerative diseases is a breakdown in communication. Even before brain cells die, the delicate machinery that keeps neurons in touch—by clearing away protein waste at the synapses—starts ...
Sep 15, 2025
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80
I recently asked myself if I'll still have a healthy brain as I get older. I hold a professorship at a neurology department. Nevertheless, it is difficult for me to judge if a particular brain, including my own, suffers from ...
Aug 19, 2025
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24
In a preclinical study, Cedars-Sinai investigators found that boosting angiotensin-converting enzyme (ACE) in key immune cells called microglia in the brain helped protect the brains of specially bred laboratory mice against ...
Aug 5, 2025
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50
A new preclinical study has found exposure to nanoplastics may contribute to the rapid progression of Alzheimer's disease and subsequent spread from the brain to other key organs such as the liver, heart and gut.
Aug 5, 2025
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56
Receiving six or more prescriptions of the drug gabapentin for low back pain is associated with significantly increased risks of developing dementia and mild cognitive impairment (MCI)—29% and 85%, respectively—finds a large ...
Jul 10, 2025
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