FDA approves Jascayd for idiopathic pulmonary fibrosis
The U.S. Food and Drug Administration has approved Jascayd (nerandomilast) tablets to treat idiopathic pulmonary fibrosis (IPF).
Oct 14, 2025
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Respiratory Tract Diseases: News and Research on Idiopathic Pulmonary Fibrosis
MeSH tree: C08.381.483.652.500
Identifying people at risk of dangerous lung scarring even before symptoms appear
UVA Health lung researchers are developing a promising approach to detecting patients at risk of interstitial lung disease (ILD), an increasingly common condition that is a leading reason for lung transplants. The approach ...
Oct 10, 2025
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CT scan changes over one year predict outcomes in fibrotic lung disease
Researchers at National Jewish Health have shown that subtle increases in lung scarring, detected by an artificial intelligence-based tool on CT scans taken one year apart, are associated with disease progression and survival ...
Oct 4, 2025
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Telomere protection failure: How genetic mutations cause pulmonary fibrosis
A research group from the National Cancer Research Center (CNIO) has found that an alteration in the POT1 gene prevents lung tissue from regenerating, which over time makes breathing difficult. The mutation prevents telomeres, ...
Sep 18, 2025
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Unexpected COPD relief: Lung fibrosis drug outperforms steroids in pre-clinical model
Researchers have found a promising treatment breakthrough for chronic obstructive pulmonary disease (COPD) that avoids many of the drawbacks of current drugs, and it has come from an unexpected place.
Aug 12, 2025
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Researchers create 3D-printed living lung tissue
UBC Okanagan researchers have developed a 3D bio-printed model that closely mimics the complexity of natural lung tissue, an innovation that could transform how scientists study lung disease and develop new treatments.
Jul 15, 2025
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Blocking little-known protein may offer hope for devastating lung disease
Researchers at the Icahn School of Medicine at Mount Sinai and collaborators have identified a previously overlooked protein, Epac1, as a key driver of idiopathic pulmonary fibrosis (IPF), a chronic and progressive lung-scarring ...
Jul 15, 2025
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Alveolar macrophage cell surface receptor TREM2 promotes lung fibrosis, study shows
Lung macrophages play a pivotal role in diseases like idiopathic pulmonary fibrosis. Two types of macrophages—the white blood cells that defend the body by killing microbes, removing dead cells and stimulating immune responses—are ...
Jul 3, 2025
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AI helps researchers understand lung disease and proposes treatment
The secrets of idiopathic pulmonary fibrosis (IPF) are written in its very name. Idiopathic refers to a disease of unknown cause, and the condition, which turns healthy lung tissue into fibrous scar tissue, still raises many ...
Jun 23, 2025
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Pulmonary fibrosis: Nerandomilast inhibits phosphodiesterase 4B, may treat multiple forms of disease
A new drug for pulmonary fibrosis has reduced disease progression by more than 50% over a 52-week treatment in two clinical trials. Pulmonary fibrosis is a very serious disease, with a life prognosis of 3 to 5 years after ...
May 21, 2025
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