MeSH tree: C12.050.351.968.934.734
A group led by the Department of Cell Biology at the Kidney Research Center, Niigata University revealed that elevated activity of cdc42 is a critical initiation event leading to proteinuria, and proposed that suppression ...
Aug 7, 2025
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The U.S. Food and Drug Administration has approved Apellis Pharmaceuticals' Empaveli (pegcetacoplan) as the first treatment for C3 glomerulopathy (C3G) or primary immune complex membranoproliferative glomerulonephritis (IC-MPGN).
Aug 4, 2025
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New 100-week data from the ongoing Phase I/II study of zigakibart, an investigational anti-APRIL monoclonal antibody, reinforce its potential as a disease-modifying treatment for IgA nephropathy (IgAN). Findings presented ...
Jun 5, 2025
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Hypertension affects more than one-third of the global adult population and is a leading contributor to early death from cardiovascular and other chronic diseases. While treatments for high blood pressure are widely available, ...
Apr 28, 2025
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Epidemiologists at the Texas A&M University School of Public Health have identified a link between arsenic and indicators of kidney disease. The research is published in the Journal of Trace Elements in Medicine and Biology.
Mar 3, 2025
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Kidney disease, leading to kidney failure, afflicts disproportionately more black people than white people. Thus, there is a huge burden of kidney health care costs among black people all over the world.
Feb 12, 2025
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Acute kidney injury (AKI) often occurs as a result of ischemia, which is a condition in which blood flow to part of the body is restricted, depriving tissues of oxygen and nutrients. This damage is commonly followed by reperfusion ...
Dec 3, 2024
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There are bidirectional associations for sleep disorders with chronic kidney disease (CKD), according to a review published in the November issue of Chronic Kidney Journal.
Nov 20, 2024
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In patients with chronic kidney disease, the loss of podocytes—part of the kidney's glomerular filtration barrier—causes irreversible disease progression. So far, physicians and researchers have found no way to effectively ...
Oct 31, 2024
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Atrasentan is associated with a significant and clinically meaningful reduction in proteinuria compared with placebo in patients with immunoglobulin A (IgA) nephropathy, according to a study published online Oct. 25 in the ...
Oct 30, 2024
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