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Nephrology news

'Toxic' molecule may play vital role in gene regulation and development

A molecule once thought to be a harmful metabolic byproduct may play a crucial role in early development and gene regulation, according to a new study published in Nature that challenges decades of biochemical assumptions. ...

A brief kidney crisis in childhood can cast a long shadow over health for years afterward

Acute kidney injury (AKI) is a condition in which the kidneys suddenly lose their ability to filter waste from the blood. Developing within hours or days, AKI can cause dangerous waste accumulation and disrupt the body's ...

Common asthma drug shows promise for reversing fatty liver

MUSC researchers are tackling MASH, or metabolic dysfunction-associated steatohepatitis, a liver disease affecting hundreds of millions worldwide. It is also a leading cause of liver transplantation, yet treatment options ...

Longer dialysis times associated with better survival

For adults undergoing maintenance in-center hemodialysis, longer dialysis times are associated with better survival, according to a study published in the June issue of Kidney International Reports.

Contrast agents in imaging—do they really harm the kidneys?

"Contrast harms the kidneys"—this belief has been present among patients for years, and sometimes also among physicians. In clinical practice, it may raise concerns about imaging examinations and procedures that use contrast ...

High levels of gut bacterial toxin trigger lupus nephritis

The body's immune reaction to increased levels of a toxic molecule, part of a bacterial species in the human gut, may reveal who is most at risk of developing lupus nephritis, according to a new study led by NYU Langone Health. ...

Transport issues disrupt dialysis for kidney patients

A new UC Davis Health study reveals that transportation challenges create major barriers for patients with end-stage kidney disease who receive hemodialysis at a clinic. These challenges also have a negative impact on dialysis ...

New biomarker for immunoglobulin A nephropathy identified

Immunoglobulin A (IgA) nephropathy is an autoimmune disease characterized by the deposition of circulating IgA-containing immune complexes (IgA-ICs) in the glomerular mesangium, leading to mesangial cell proliferation, enhanced ...

I'm a kidney surgeon: Here's why I hope I never see you

As a urological surgeon, I meet many patients with chronic (long-term) kidney disease. Sometimes, I see patients that have progressed to the point where their kidneys do not work at all. This leads to the toxic build-up of ...

Hidden acid imbalance in kidney disease raises red flags

A Japanese registry has identified a blind spot in the routine care of patients with chronic kidney disease (CKD). Serum bicarbonate levels are rarely measured, leaving metabolic acidosis largely undetected and hence, undertreated.