Immunotherapy resistance in kidney cancer driven by myeloid cell signaling
Immunotherapy with immune checkpoint inhibitors is standard first-line treatment for advanced renal cell carcinoma (RCC), but not every patient responds.
Nov 3, 2025
0
25
Nephrology news
Lupus low disease activity state attainable in lupus nephritis
In lupus nephritis, attainment of complete renal response (CRR)/partial renal response (PRR) and lupus low disease activity state (LLDAS) is associated with best relapse-free survival, with independent associations seen with ...
Aug 14, 2025
0
25
Kidney transplant waitlisting: A potentially better way to optimize the timing
The current kidney transplant waitlisting criterion is based on a single measurement of kidney function (estimated glomerular filtration rate [eGFR] ≤20 ml/min/1.73 m2) and does not consider an individual's risk of progressing ...
Nov 8, 2025
0
23
Research shows how immune system reacts to pig kidney transplants in living patients
Novel research led by Brazilian scientists describes the immune system's reactions in detail in the first living patient to receive a genetically modified pig kidney transplant. This paves the way for the search for therapies ...
Jan 8, 2026
0
24
Cardiovascular–kidney–metabolic syndrome may shorten your life expectancy
A study involving more than half a million adults has confirmed that the combination of cardiovascular, kidney, and metabolic conditions, collectively known as cardiovascular–kidney–metabolic (CKM) syndrome, substantially ...
Sep 23, 2025
0
23
New pill lowers stubborn BP in kidney patients
A novel pill that blocks the hormone aldosterone shows promise for lowering blood pressure and potentially delaying the progression of kidney disease in people with both conditions.
Sep 14, 2025
0
23
Dietary patterns linked to chronic kidney disease risk
Compared with other dietary indices, Dietary Approaches to Stop Hypertension (DASH) and the Dietary Inflammatory Index (DII) provide chronic kidney disease (CKD) risk discrimination, according to a study published online ...
Aug 14, 2025
0
22
Gene editing may represent a new way to treat inherited kidney disease
Researchers in Berlin have used base editing to repair mutations that cause the kidney disorder ADPKD in cells from both mice and humans. In mice, a team led by Michael Kaminski was able to ease a key symptom of the difficult-to-treat ...
Sep 17, 2025
0
22
How mutations in bodily tissues affect aging
Two new studies from Karolinska Institutet in Sweden have investigated how mutations that occur in muscles and blood vessels over time can affect aging. The studies, which are published in Nature Aging, show that such mutations ...
Aug 20, 2025
0
63
Q&A: How organoids could make gene therapy trials safer by identifying hidden risks early on
Ryuji Morizane, MD, Ph.D., of the Department of Medicine at Massachusetts General Hospital, is the senior/corresponding author of a new paper published in Signal Transduction and Targeted Therapy, titled "AAV for gene therapy ...
Aug 19, 2025
0
22
