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Diseases, Conditions, Syndromes
First-ever effective therapy for rare, devastating neurodegenerative mitochondrial diseases
A new treatment could improve the lives of patients with mitochondrial diseases called POLG-related disorders, according to a unique clinical trial led by the Research Institute of the McGill University Health Center (RI-MUHC). ...
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Central nervous system-associated macrophages could modulate post-stroke immune responses
An ischemic stroke is a type of stroke that occurs when a blood clot in an artery, also known as thrombus, or the progressive narrowing of arteries, blocks the blood and oxygen flowing to the brain. This process can cause ...
Building bridges between cells for brain health: Research finds microglia rescue neurons through tunneling nanotubes
The brain contains many cell types, from the prominent neurons to the lesser-known microglia. The latter are integral to the brain's immune system and play a crucial role as the brain's cleanup crew. A recent study conducted ...
Jul 26, 2024
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'Prelude' to neuromuscular disease spinal muscular atrophy may offer chances for better treatment
Spinal muscular atrophy (SMA) is a severe neurological disease for which there is presently no cure, although current therapies can alleviate symptoms. In the search for better treatment options, scientists at DZNE and the ...
Jul 26, 2024
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Mitochondria support immune response to central nervous system injuries, scientists discover
Northwestern Medicine scientists have discovered that mitochondria are not necessary for the proliferation of specialized immune cells in the central nervous system, but do help those cells respond to demyelinating injuries, ...
Jul 26, 2024
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A new therapeutic target offers a promising pathway for multiple sclerosis treatment
Researchers from Kyushu University have identified a potential therapeutic target for the treatment of advanced multiple sclerosis (MS), a potentially disabling condition associated with the central nervous system.
Jul 26, 2024
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Researchers find increased activity in part of the subthalamus during mouse mother/pup interactions
A combined team of physiologists and medical researchers from Yale University and Sorbonne Université, ICM, has found a part of the mouse brain that becomes more active when mothers and their pups interreact.
Does organizing your page help organize your mind?
If you have ever wondered how you manage to keep track of the immense amount of information coming to you each day, you might want to thank the positional tagging system in your mind.
Jul 26, 2024
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What happens in the brain during a migraine? And what medications can be used to treat it?
Migraine is many things, but one thing it's not is "just a headache."
Jul 26, 2024
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How epigenetics influence memory formation
When we form a new memory, the brain undergoes physical and functional changes known collectively as a "memory trace." A memory trace represents the specific patterns of activity and structural modifications of neurons that ...
Jul 25, 2024
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Machine learning shows potential for predicting multiple sclerosis progression
Machine learning models can reliably inform clinicians about the disability progression of multiple sclerosis, according to a study published in the open-access journal PLOS Digital Health by Edward De Brouwer of KU Leuven, ...
Jul 25, 2024
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Cancer drug could ease cognitive function for some with autism
An experimental cancer drug could make thinking easier for individuals with Rett syndrome, a rare disorder linked to autism, according to new research from the University of California San Diego—a discovery that could lead ...
Jul 25, 2024
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Chaotic dynamics in the brain may enable probabilistic thinking
Chaos may be behind the brain's ability to compute probabilities, according to a new analysis by two neuroscientists at RIKEN. The research is published in the Proceedings of the National Academy of Sciences.
Jul 25, 2024
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Cell aging discovery could help detect early warning signs for neurodegenerative diseases
A team from King's College London and collaborators have pinpointed how different areas of the neuron age differently, with a potential knock-on effect on healthy cell function and the development of neurodegenerative conditions. ...
Jul 25, 2024
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Antisense oligonucleotide treatment shows promise in treating Parkinson's disease progression
Parkinson's disease (PD), as well as many other neurodegenerative disorders, has shown a link between the abnormal aggregation of a protein called α-synuclein (aSyn) and neuronal death. These aggregates, known as Lewy bodies ...
Jul 25, 2024
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Exploring consciousness with 'eureka' moments
For generations, researchers have been pondering the question of how and where consciousness is formed in the brain. Professor Ekrem Dere from Ruhr University Bochum, Germany, proposes a new approach to researching conscious ...
Jul 25, 2024
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Scientists create novel anti-thrombogenic coatings to overcome endovascular therapy challenges
A researcher at AIST, in collaboration with the Japan Medical Startup Incubation Program (JMPR) and N.B. Medical Corporation, has developed a novel anti-thrombogenic coating for stents used in the treatment of intracranial ...
Jul 25, 2024
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Researchers close in on new technology for objectively measuring pain
On a scale of one to ten, how much pain do you feel?
Jul 25, 2024
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Alterations in T cell subpopulations links to brain structure in tardive dyskinesia
Alterations in the proportion of T cell subpopulations are associated with brain structural abnormalities in patents with schizophrenia with tardive dyskinesia (TD), according to a study published in the July issue of Schizophrenia ...
Jul 25, 2024
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Transcranial magnetic stimulation shows promise for treatment-resistant depression biotype
Depression is one of the most common mental health disorders worldwide, estimated to affect about one in eight people worldwide. Once individuals experiencing symptoms of depression approach a psychiatrist or psychotherapist, ...
Daily rhythms depend on receptor density in biological clock, study shows
In humans and other animals, signals from a central circadian clock in the brain generate the seasonal and daily rhythms of life. They help the body to prepare for expected changes in the environment and also optimize when ...
Jul 24, 2024
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Neuroscientists discover brain circuitry of placebo effect for pain relief
The placebo effect is very real. This we've known for decades, as seen in real-life observations and the best double-blinded randomized clinical trials researchers have devised for many diseases and conditions, especially ...
Jul 24, 2024
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New research offers insight on preventing brain damage in preterm babies
Mark Petersen, MD, has seen firsthand the devastating effects of brain bleeds in premature babies. It's an exceedingly common condition that affects up to 20% of infants born before 28 weeks of gestation, bringing an increased ...
Jul 24, 2024
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Improving interoception: Researchers find audiovisual breathing enhances bodily awareness
A new study conducted at Reichman University's Baruch Ivcher Institute for Brain, Cognition, and Technology, led by Prof. Amir Amedi, demonstrates how the external representation of physiological signals (interoception) can ...
Jul 24, 2024
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