Brain abnormalities found in people with writer's cramp

July 23, 2007

People with serious cases of writer’s cramp have brain abnormalities, according to a study published in the July 24, 2007, issue of Neurology, the medical journal of the American Academy of Neurology. People with writer’s cramp had less brain tissue than healthy people in three areas of the brain that connect the senses and movement with their affected hand.

Writer’s cramp is a form of dystonia, an involuntary, sustained muscle contraction. Writer’s cramp often occurs in people who have used the same muscles repeatedly for years.

The study involved 30 people who had writer’s cramp for an average of seven years with no other forms of dystonia. Using brain imaging, the researchers compared the brains of those with writer’s cramp to 30 healthy people.

The researchers found that those with writer’s cramp had less grey matter in three areas of the brain: the cerebellum, the thalamus, and the sensorimotor cortex.

“It’s not clear whether these abnormalities are a cause or a result of the disease,” said study author Stéphane Lehéricy, MD, PhD, of Salpêtrière Hospital in Paris, France. “The fact that the brain abnormalities are in the areas that control the affected hand suggests that these differences are specific to this problem.”

“Another theory is that the brain structure changed and adapted as a result of the sustained repetitive movement,” Lehéricy said. “Studies have shown that people with no dystonia can experience brain changes due to learning new information, which supports this theory.”

Source: American Academy of Neurology

Explore further: Why do healthy people have harmful mutations?

Related Stories

Recommended for you

Lab grown human colons change study of GI disease

June 22, 2017

Scientists used human pluripotent stem cells to generate human embryonic colons in a laboratory that function much like natural human tissues when transplanted into mice, according to research published June 22 in Cell Stem ...

Paracetamol during pregnancy can inhibit masculinity

June 22, 2017

Paracetamol is popular for relieving pain. But if you are pregnant, you should think twice before popping these pills according to the researchers in a new study. In an animal model, Paracetamol, which is the pain-relieving ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.