Treatment of Helicobacter pylori-negative gastric MALT lymphoma

May 7, 2010

A research team from South Korea evaluated the treatment outcome of Helicobacter pylori (H. pylori)-negative low-grade gastric mucosa associated lymphoid tissue (MALT) lymphoma patients to offer therapeutic guidelines for such patients. Their results showed that eradication therapy may be offered as an initial treatment option even in cases of localized H. pylori-negative gastric MALT lymphoma.

Eradication of (H. pylori) is a well-accepted initial therapy in cases of localized (stage ⅠE) low-grade gastric mucosa-associated lymphoid tissue (MALT) lymphoma associated with H. pylori infection. However, there are no treatment guidelines for the management of H. pylori-negative low-grade gastric MALT lymphoma.

Retrospectively reviewing the clinical outcome and clinicopathologic factors of stage ⅠE H. pylori-negative low-grade gastric MALT lymphoma cases from August 1998 to June 2009, a research team from South Korea analyzed the treatment outcome of H. pylori-negative low-grade gastric MALT lymphoma. Their study will be published on May 7, 2010 in the World Journal of Gastroenterology .

Their results indicated that H. pylori eradication therapy may be an initial treatment option for localized H. pylori-negative gastric MALT lymphoma. Their study adds information which helps in the establishment of strategies for patients with localized H. pylori-negative gastric MALT .

More information: Park HS, Kim YJ, Yang WI, Suh CO, Lee YC. Treatment outcome of localized Helicobacter pylori-negative low-grade gastric MALT lymphoma. World J Gastroenterol 2010; 16(17): 2158-2162. www.wjgnet.com/1007-9327/full/v16/i17/2158.htm

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