Features of the metabolic syndrome common in persons with psoriasis

December 20, 2010

Individuals with psoriasis have a high prevalence of the metabolic syndrome, according to a report posted online today that will appear in the April 2011 print issue of Archives of Dermatology.

According to background information in the article, individual features of the include obesity, , diabetes and high total cholesterol and triglycerides. Additional background information notes that while past studies have suggested a link between and individual components of the metabolic syndrome, there is little data available regarding the association between psoriasis and the metabolic syndrome as a whole.

Using data from the National Health and Nutrition Examination Survey, Thorvardur Jon Love, M.D., of Landspitali University Hospital, Reykjavik, Iceland, and colleagues, examined the association between psoriasis and the metabolic syndrome. The study included 6,549 individuals, and the mean (average) age of participants was 39, half were men and the mean (BMI) was 28.

Overall, 40 percent of individuals with psoriasis also had features of the metabolic syndrome, compared with 23 percent among controls. The most common feature of the metabolic syndrome among individuals with psoriasis was abdominal obesity (63 percent), followed by high triglyceride levels (44 percent) and low levels of high-density lipoprotein (HDL) or "good" cholesterol (34 percent). High triglyceride levels are defined as at or above 150 milligrams per deciliter, and low HDL levels are defined as less than 40 milligrams per deciliter in men and less than 50 milligrams per deciliter in women. No elements of the metabolic syndrome were found in 28 percent of individuals without psoriasis compared with 13 percent of those with psoriasis.

"In conclusion, these findings from a nationally representative sample of U.S. adults show a doubling in the prevalence of the metabolic syndrome among patients with psoriasis independent of age, sex, race/ethnicity and C-reactive protein levels," the authors write.

"Given its associated serious complications, this comorbidity needs to be recognized and taken into account when treating individuals with psoriasis," they conclude.

More information: Arch Dermatol. Published online December 20, 2010. doi:10.1001/archdermatol.2010.370

Related Stories

Recommended for you

Four simple tests could help GPs spot pneumonia and reduce unnecessary antibiotics

November 23, 2017
Testing for fever, high pulse rate, crackly breath sounds, and low oxygen levels could be key to helping GPs distinguish pneumonia from less serious infections, according to a large study published in the European Respiratory ...

New approach to tracking how deadly 'superbugs' travel could slow their spread

November 22, 2017
Killer bacteria - ones that have out-evolved our best antibiotics—may not go away anytime soon. But a new approach to tracking their spread could eventually give us a fighting chance to keep their death toll down.

Research points to diagnostic test for top cause of liver transplant in kids

November 22, 2017
Biliary atresia is the most common cause of liver transplants for children in the United States. Now researchers report in Science Translational Medicine finding a strong biomarker candidate that could be used for earlier ...

Metabolites altered in chronic kidney disease

November 22, 2017
Chronic kidney disease (CKD) affects 1 in 7 people in the United States, according to the U.S. National Institute of Diabetes & Digestive & Kidney Diseases (NIDDK). These individuals have a very high risk of cardiovascular ...

Alcohol consumption and metabolic factors act together to increase the risk of severe liver disease

November 22, 2017
A new study provides insights into the interaction between alcohol consumption and metabolic factors in predicting severe liver disease in the general population. The findings, which are published in Hepatology, indicate ...

Rainfall can indicate that mosquito-borne epidemics will occur weeks later

November 22, 2017
A new study demonstrates that outbreaks of mosquito-borne viruses Zika and Chikungunya generally occur about three weeks after heavy rainfall.Researchers also found that Chikungunya will predominate over Zika when both circulate ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.