Impact of timing on carotid artery stenting after stroke or transient ischemic attack

November 14, 2011

A recent study found no significant difference in the outcome for patients who received carotid artery stenting (CAS) at more than 30 days post-transient ischemic attack (TIA) or stroke versus those who received CAS at 30 days or less post-event.

Surgical literature recommends that the removal of plaque from the carotid artery take place within 14 days of a TIA or stroke for the best outcomes. However, little is known about the optimal timing of carotid artery stenting for these patients.

Nicholas J. Ruggiero, II, M.D., F.A.C.C., F.S.C.A.I., F.S.V.M., director of Structural Heart Disease and Non-Coronary Interventions at the Jefferson Heart Institute and assistant professor of Medicine, Jefferson Medical College of Thomas Jefferson University, led a multi-site team of researchers who attempted to uncover the optimal timing for carotid artery stenting after TIA or stroke. He will present their abstract at the annual meeting on November 14 at 9:30 AM in Orlando, FL.

"We hope for the results of this study to serve as a guide for the appropriate timing and use for CAS," said Ruggiero.

The team retrospectively evaluated 899 symptomatic patients in the NCDR CARE (R) Registry who underwent CAS from January 2005 to February 2011. They compared baseline characteristics, including procedural, in-hospital and 30-day events, including TIA, stroke, heart attack or neurologic death.

Of the 899 patients, 614 received CAS at 30 days or less post-event and 285 at more than 30 days. The demographics of each patient population were evenly matched, except for higher a prevalence of smoking, abnormal lipid levels, COPD, and use of () in the group that received CAS at greater than 30 days, and a higher occurrence of in the 30 days or less group.

"This study suggests that the optimal timing of CAS in symptomatic patients can be individualized and performed safely, but further studies are necessary to substantiate this," said Ruggiero.

Explore further: Researchers study outcomes of carotid artery stenting following prior carotid procedure

Related Stories

Researchers study outcomes of carotid artery stenting following prior carotid procedure

November 14, 2011
A new study shows that carotid artery stenting (CAS) following prior same-side carotid artery revascularization is safe, effective and results in lower incidences of in-hospital death, stroke and heart attack compared to ...

Results of the PROFI study reported at TCT 2011

November 12, 2011
Results from the PROFI study indicate that the use of a proximal balloon occlusion in carotid artery stenting lead to fewer cerebral ischemic lesions – a predictor of stroke – than with the use of a filter. Trial ...

Recommended for you

Could aggressive blood pressure treatments lead to kidney damage?

July 18, 2017
Aggressive combination treatments for high blood pressure that are intended to protect the kidneys may actually be damaging the organs, new research from the University of Virginia School of Medicine suggests.

Quantifying effectiveness of treatment for irregular heartbeat

July 17, 2017
In a small proof-of-concept study, researchers at Johns Hopkins report a complex mathematical method to measure electrical communications within the heart can successfully predict the effectiveness of catheter ablation, the ...

Concerns over side effects of statins stopping stroke survivors taking medication

July 17, 2017
Negative media coverage of the side effects associated with taking statins, and patients' own experiences of taking the drugs, are among the reasons cited by stroke survivors and their carers for stopping taking potentially ...

Study discovers anticoagulant drugs are being prescribed against safety advice

July 17, 2017
A study by researchers at the University of Birmingham has shown that GPs are prescribing anticoagulants to patients with an irregular heartbeat against official safety advice.

Protein may protect against heart attack

July 14, 2017
DDK3 could be used as a new therapy to stop the build-up of fatty material inside the arteries

Heart study finds faulty link between biomarkers and clinical outcomes

July 14, 2017
Surrogate endpoints (biomarkers), which are routinely used in clinical research to test new drugs, should not be trusted as the ultimate measure to approve new health interventions in cardiovascular medicine, according to ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.