Dose-Response link between tanning bed use, skin cancer

February 28, 2012
Dose-Response link between tanning bed use, skin cancer

(HealthDay) -- Use of tanning beds, especially in high school and college, is associated with an increased risk of skin cancer, according to a study published online Feb. 27 in the Journal of Clinical Oncology.

Mingfeng Zhang, M.D., from Brigham and Women's Hospital in Boston, and colleagues conducted a prospective observational study of 73,494 female nurses, from 1989 to 2009, to investigate whether the frequency of tanning bed use during high school/college and at ages 25 to 35 correlated with the risk of skin cancer. Models were adjusted for host risk factors, sun exposure behaviors at a young age, and ultraviolet index of residence.

During follow-up, the researchers found that 5,506 nurses were diagnosed with (BCC), 403 with (SCC), and 349 with melanoma. For an incremental increase in use of tanning beds of four times per year during both periods, the multivariable-adjusted hazard ratio (HR) of was 1.15 for BCC (P < 0.001), 1.15 for SCC (P = 0.03), and 1.11 for melanoma (P = 0.13). There was a significantly higher risk of BCC associated with the use of tanning beds more than six times per year compared with no use during high school/college compared with use at ages 25 to 35 (HR, 1.73 versus 1.28; P for heterogeneity < 0.001)

"These findings provide evidence to support warning the public against future use of and enacting state and federal legislation to ban tanning bed use for those under age 18," the authors write.

Explore further: Increased tanning bed use increases risk for deadly skin cancers

More information: Abstract
Full Text

Related Stories

Increased tanning bed use increases risk for deadly skin cancers

October 24, 2011
Researchers confirmed an association between tanning bed use and an increased risk for three common skin cancers — basal cell carcinoma, squamous cell carcinoma and melanoma, according to results presented at the 10th ...

Tanning beds could provide a greater risk than originally thought: new study

October 10, 2011
(Medical Xpress) -- A new study published in the Journal of Investigative Dermatology has found that, despite previous information, the UVA radiation used in tanning beds may cause more damage to the skin that was originally ...

Tanning bed users exhibit brain changes and behavior similar to addicts

August 10, 2011
People who frequently use tanning beds may be spurred by an addictive neurological reward-and-reinforcement trigger, researchers at UT Southwestern Medical Center have found in a pilot study.

Resist temptation to tan, despite winter doldrums

December 30, 2011
(Medical Xpress) -- Don’t let winter’s lack of sunshine lure you into a tanning bed. 

Recommended for you

Alternative splicing, an important mechanism for cancer

September 22, 2017
Cancer, which is one of the leading causes of death worldwide, arises from the disruption of essential mechanisms of the normal cell life cycle, such as replication control, DNA repair and cell death. Thanks to the advances ...

'Labyrinth' chip could help monitor aggressive cancer stem cells

September 21, 2017
Inspired by the Labyrinth of Greek mythology, a new chip etched with fluid channels sends blood samples through a hydrodynamic maze to separate out rare circulating cancer cells into a relatively clean stream for analysis. ...

Drug combination may improve impact of immunotherapy in head and neck cancer

September 21, 2017
Checkpoint inhibitor-based immunotherapy has been shown to be very effective in recurrent and metastatic head and neck cancer but only in a minority of patients. University of California San Diego School of Medicine researchers ...

Whole food diet may help prevent colon cancer, other chronic conditions

September 21, 2017
A diet that includes plenty of colorful vegetables and fruits may contain compounds that can stop colon cancer and inflammatory bowel diseases in pigs, according to an international team of researchers. Understanding how ...

New kinase detection method helps identify targets for developing cancer drugs

September 21, 2017
Purdue University researchers have developed a high-throughput method for matching kinases to the proteins they phosphorylate, speeding the ability to identify multiple potential cancer drug targets.

Poliovirus therapy induces immune responses against cancer

September 20, 2017
An investigational therapy using modified poliovirus to attack cancer tumors appears to unleash the body's own capacity to fight malignancies by activating an inflammation process that counter's the ability of cancer cells ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.