MR enterography is as good or better than standard imaging exams for pediatric Crohn's patients

April 30, 2012

MR enterography is superior to CT enterography in diagnosing fibrosis in pediatric patients with Crohn disease and equally as good as CT enterography in detecting active inflammation, and a new study shows.

The study, conducted at Massachusetts General Hospital in Boston, found that MR enterography was 77.6% accurate in depicting compared to 56.9% for CT enterography. MR enterography had an 82.1% accuracy rate versus 77.6% accuracy rate for CT enterography for detecting active inflammation, said Keith Quencer, MD, one of the authors of the study. The study included 23 with Crohn disease. All patients had both a CT enterography and MR enterography examination.

Accurately identifying fibrosis or inflammation in these patients is key to determining appropriate treatment, said Dr. Quencer. Pediatric Crohn's patients often have nonspecific symptoms. If their symptoms are due to inflammation, then is appropriate, said Dr. Quencer. On the other hand, if the symptoms are due to from fibrosis, then a surgical approach may be necessary, he said.

"While our study shows that MR enterography is as good or better than CT enterography, CT enterography is faster than MR enterography, less expensive and more widely available," Dr. Quencer said. CT enterography remains the preferred imaging modality to evaluate Crohn disease.

"We are seeing a change in our practice though," he added, "in part because MR enterography does not use radiation. "Crohn disease is a chronic disease, with patients often requiring frequent imaging studies due to symptom recurrence. As we strive to minimize , particularly in the pediatric population, MR enterography should be considered, Dr. Quencer said.

Explore further: MR enterography as effective as CT in diagnosing Crohn's disease, reduces radiation exposure

Related Stories

Recommended for you

Ancient stress response provides clues to cancer resistance

April 25, 2017

Cancer is often able to craftily outwit the best techniques modern medicine has developed to treat it. In an attempt to understand and combat cancer's vaunted prowess, an unusual collaboration between physicists and a leading ...

Studying a catalyst for blood cancers

April 25, 2017

Imagine this scenario on a highway: A driver starts to make a sudden lane change but realizes his mistake and quickly veers back, too late. Other motorists have already reacted and, in some cases, collide. Meanwhile, the ...

Savior of T-cells may be enemy of liver immune cells

April 24, 2017

Researchers at Houston Methodist demonstrated that a surface protein called OX40, responsible for keeping one type of immune system cell alive, can trigger the death of liver immune cells, in turn starting a chain reaction ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.