Cataract risk up for statin users with type 2 diabetes

August 13, 2012
Cataract risk up for statin users with type 2 diabetes
Statin use, which is substantially higher in patients with type 2 diabetes, correlates with an increased risk of age-related cataracts, according to a study published in the August issue of Optometry and Vision Science.

(HealthDay) -- Statin use, which is substantially higher in patients with type 2 diabetes, correlates with an increased risk of age-related (AR) cataracts, according to a study published in the August issue of Optometry and Vision Science.

Noting that diabetes is a risk factor for AR , Carolyn M. Machan, O.D., from the University of Waterloo in Canada, and colleagues examined the association between AR cataract, , and reported statin use in a large cohort. The prevalence of statin use was assessed for the 452 patients with type 2 diabetes and the 5,884 patients without diabetes.

The researchers found that, for patients older than 38 years, the prevalence of statin use was 56 percent for those with type 2 diabetes and 16 percent for those without diabetes. There was a significant correlation between type 2 diabetes and nuclear sclerosis (odds ratio [OR], 1.62) and (OR, 1.37). There was a significant correlation between statin use and nuclear sclerosis and posterior subcapsular cataract (OR, 1.48 for both). In statin users the 50 percent probability of cataract occurred at age 51.7 for those with type 2 diabetes and at age 54.9 for those without diabetes. The ages were significantly older (55.1 and 57.3 years, respectively) for non-statin users.

"Regardless of the outcome of further study, the benefits of statin use in people with type 2 diabetes are anticipated to continue to outweigh any associated increased risk of AR cataract," the authors write. "Information provided here can serve public health efforts to educate people on the risks of treatments associated with type 2 diabetes."

Explore further: Statin use in postmenopausal women associated with increased diabetes risk

More information: Abstract
Full Text

Related Stories

Statin use in postmenopausal women associated with increased diabetes risk

January 9, 2012
The use of statins in postmenopausal women is associated with increased diabetes risk, according to a study published Online First by the Archives of Internal Medicine.

Intensive-dose statin therapy associated with increased risk of diabetes

June 21, 2011
An analysis of data from previously published studies indicates that intensive-dose statin therapy is associated with an increased risk of new-onset diabetes compared with moderate-dose therapy, according to a study in the ...

Type 2 diabetes linked to higher risk of stroke and CV problems; metabolic syndrome isn't

June 13, 2011
Among patients who have had an ischemic stroke or transient ischemic attack (TIA), type 2 diabetes was associated with an increased risk of recurrent stroke or cardiovascular events, but metabolic syndrome was not, according ...

Cardiovascular benefits of taking statins outweigh diabetes risk

August 9, 2012
The benefits of taking statins to reduce the risk of cardiovascular disease outweigh the increased risk of developing diabetes experienced by some patients who take these cholesterol-lowering drugs, according to an Article ...

Polycystic ovarian syndrome ups risk of type 2 diabetes

June 22, 2012
(HealthDay) -- Middle-aged women with polycystic ovary syndrome (PCOS) are at increased risk of developing type 2 diabetes, according to a prospective long-term study published online June 14 in Diabetes.

Recommended for you

Genetic discovery may help better identify children at risk for type 1 diabetes

January 17, 2018
Six novel chromosomal regions identified by scientists leading a large, prospective study of children at risk for type 1 diabetes will enable the discovery of more genes that cause the disease and more targets for treating ...

Thirty-year study shows women who breastfeed for six months or more reduce their diabetes risk

January 16, 2018
In a long-term national study, breastfeeding for six months or longer cuts the risk of developing type 2 diabetes nearly in half for women throughout their childbearing years, according to new Kaiser Permanente research published ...

Women who have gestational diabetes in pregnancy are at higher risk of future health issues

January 16, 2018
Women who have gestational diabetes mellitus (GDM) during pregnancy have a higher than usual risk of developing type 2 diabetes, hypertension, and ischemic heart disease in the future, according to new research led by the ...

Diabetes gene found that causes low and high blood sugar levels in the same family

January 15, 2018
A study of families with rare blood sugar conditions has revealed a new gene thought to be critical in the regulation of insulin, the key hormone in diabetes.

Discovery could lead to new therapies for diabetics

January 12, 2018
New research by MDI Biological Laboratory scientist Sandra Rieger, Ph.D., and her team has demonstrated that an enzyme she had previously identified as playing a role in peripheral neuropathy induced by cancer chemotherapy ...

Enzyme shown to regulate inflammation and metabolism in fat tissue

January 11, 2018
The human body has two primary kinds of fat—white fat, which stores excess calories and is associated with obesity, and brown fat, which burns calories in order to produce heat and has garnered interest as a potential means ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.