Arterial stiffness inversely tied to plasma adiponectin levels

September 27, 2012
Arterial stiffness inversely tied to plasma adiponectin levels
Arterial stiffness is inversely related to plasma adiponectin levels in young, normotensive patients with type 1 diabetes, according to a study published online Sept. 21 in Diabetes Care.

(HealthDay)—Arterial stiffness is inversely related to plasma adiponectin levels in young, normotensive patients with type 1 diabetes, according to a study published online Sept. 21 in Diabetes Care.

By measuring carotid-femoral pulse wave velocity (PWV), Afroditi Tsiakou, M.D., from the Athens University Medical School in Greece, and colleagues assessed large artery stiffness in normotensive patients with up to the age of 40.

The researchers found that the 80 patients (39 men) who were included in the analysis were characterized as having an age of 27.1 ± 6.1 years; a of 24.2 ± 3.1 kg/m²; a glycated of 7.5 ±1.6 percent; an adiponectin level of 13.9 ± 6.7 µg/mL; and PWV of 5.6 ± 0.9 m/s. There was a significant, inverse correlation of log adiponectin with age-adjusted PWV and .

"Arterial stiffness is inversely related to adiponectin concentration in young patients with type 1 diabetes without major complications," the authors write. "Future studies may assess adiponectin at diagnosis of diabetes and after cardiovascular events, while randomized trials could target increasing adiponectin in patients with type 1 diabetes and low adiponectin."

Explore further: Metabolic syndrome linked to arterial stiffness in CKD

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Metabolic syndrome linked to arterial stiffness in CKD

June 4, 2012
(HealthDay) -- For patients with chronic kidney disease (CKD), those with metabolic syndrome (MetS) have increased arterial stiffness but no increase in endothelial dysfunction, compared to those without MetS, according to ...

Another potential risk factor for developing dementia and Alzheimer's disease in women

January 2, 2012
A hormone derived from visceral fat called adiponectin may play a role as a risk factor for development of all-cause dementia and Alzheimer disease (AD) in women, according to a study published Online First by the Archives ...

Researchers iron out the link between serum ferritin and diabetes

September 10, 2012
Iron overload increases the risk for insulin resistance and type 2 diabetes; however, the exact mechanisms that link the two are unknown.

Maternal glycemic status linked to epigenetic changes

March 9, 2012
(HealthDay) -- Maternal glycemic status and adiponectin levels are linked to epigenetic changes in the adiponectin gene (ADIPOQ), according to a study published online March 6 in Diabetes.

Nutrition type affects endocrinology in SGA infants

August 1, 2012
(HealthDay) -- Small-for-gestational-age (SGA) infants who are formula-fed (FOF) have elevated endocrine levels of high-molecular-weight (HMW) adiponectin and insulin growth factor-I (IGF-I) compared with breastfed (BRF) ...

Recommended for you

Pre-diabetes discovery marks step towards precision medicine

November 20, 2017
Researchers from the University of Sydney's Charles Perkins Centre have identified three specific molecules that accurately indicate insulin resistance, or pre-diabetes - a major predictor of metabolic syndrome, the collection ...

Scientists reverse diabetes in a mouse model using modified blood stem cells

November 15, 2017
Researchers at Boston Children's Hospital have successfully reversed type 1 diabetes in a mouse model by infusing blood stem cells pre-treated to produce more of a protein called PD-L1, which is deficient in mice (and people) ...

Pregnancy-related conditions taken together leave moms—and dads—at risk

November 14, 2017
Research has already shown that women who develop either diabetes or high blood pressure during pregnancy are at risk of getting type 2 diabetes, high blood pressure or heart disease years later. Now, a new study from a team ...

Study reveals how a very low calorie diet can reverse type 2 diabetes

November 9, 2017
In a new study, a Yale-led research team uncovers how a very low calorie diet can rapidly reverse type 2 diabetes in animal models. If confirmed in people, the insight provides potential new drug targets for treating this ...

Targeting a microRNA shows potential to enhance effectiveness of diabetes drugs

November 7, 2017
Over the past 15 years, University of Alabama at Birmingham endocrinologist Anath Shalev, M.D., has unraveled a crucial biological pathway that malfunctions in diabetes.

Researchers link Western diet to vascular damage and prediabetes

October 31, 2017
Could short-term exposure to the average American diet increase one's risk for developing diabetes and cardiovascular disease? According to a recent study funded by the American Heart Association (AHA), researchers from New ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.