Arterial stiffness inversely tied to plasma adiponectin levels

September 27, 2012
Arterial stiffness inversely tied to plasma adiponectin levels
Arterial stiffness is inversely related to plasma adiponectin levels in young, normotensive patients with type 1 diabetes, according to a study published online Sept. 21 in Diabetes Care.

(HealthDay)—Arterial stiffness is inversely related to plasma adiponectin levels in young, normotensive patients with type 1 diabetes, according to a study published online Sept. 21 in Diabetes Care.

By measuring carotid-femoral pulse wave velocity (PWV), Afroditi Tsiakou, M.D., from the Athens University Medical School in Greece, and colleagues assessed large artery stiffness in normotensive patients with up to the age of 40.

The researchers found that the 80 patients (39 men) who were included in the analysis were characterized as having an age of 27.1 ± 6.1 years; a of 24.2 ± 3.1 kg/m²; a glycated of 7.5 ±1.6 percent; an adiponectin level of 13.9 ± 6.7 µg/mL; and PWV of 5.6 ± 0.9 m/s. There was a significant, inverse correlation of log adiponectin with age-adjusted PWV and .

"Arterial stiffness is inversely related to adiponectin concentration in young patients with type 1 diabetes without major complications," the authors write. "Future studies may assess adiponectin at diagnosis of diabetes and after cardiovascular events, while randomized trials could target increasing adiponectin in patients with type 1 diabetes and low adiponectin."

Explore further: Metabolic syndrome linked to arterial stiffness in CKD

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Metabolic syndrome linked to arterial stiffness in CKD

June 4, 2012
(HealthDay) -- For patients with chronic kidney disease (CKD), those with metabolic syndrome (MetS) have increased arterial stiffness but no increase in endothelial dysfunction, compared to those without MetS, according to ...

Another potential risk factor for developing dementia and Alzheimer's disease in women

January 2, 2012
A hormone derived from visceral fat called adiponectin may play a role as a risk factor for development of all-cause dementia and Alzheimer disease (AD) in women, according to a study published Online First by the Archives ...

Researchers iron out the link between serum ferritin and diabetes

September 10, 2012
Iron overload increases the risk for insulin resistance and type 2 diabetes; however, the exact mechanisms that link the two are unknown.

Maternal glycemic status linked to epigenetic changes

March 9, 2012
(HealthDay) -- Maternal glycemic status and adiponectin levels are linked to epigenetic changes in the adiponectin gene (ADIPOQ), according to a study published online March 6 in Diabetes.

Nutrition type affects endocrinology in SGA infants

August 1, 2012
(HealthDay) -- Small-for-gestational-age (SGA) infants who are formula-fed (FOF) have elevated endocrine levels of high-molecular-weight (HMW) adiponectin and insulin growth factor-I (IGF-I) compared with breastfed (BRF) ...

Recommended for you

Alzheimer's drug cuts hallmark inflammation related to metabolic syndrome by 25 percent

July 20, 2017
An existing Alzheimer's medication slashes inflammation and insulin resistance in patients with metabolic syndrome, a potential therapeutic intervention for a highly dangerous condition affecting 30 percent of adults in the ...

Diabetes or its precursor affects 100 million Americans

July 19, 2017
Almost one-third of the US population—100 million people—either has diabetes or its precursor condition, known as pre-diabetes, said a government report Tuesday.

One virus may protect against type 1 diabetes, others may increase risk

July 11, 2017
Doctors can't predict who will develop type 1 diabetes, a chronic autoimmune disease in which the immune system destroys the cells needed to control blood-sugar levels, requiring daily insulin injections and continual monitoring.

Diabetes complications are a risk factor for repeat hospitalizations, study shows

July 7, 2017
For patients with diabetes, one reason for hospitalization and unplanned hospital readmission is severe dysglycemia (uncontrolled hyperglycemia - high blood sugar, or hypoglycemia - low blood sugar), says new research published ...

Researchers identify promising target to protect bone in patients with diabetes

July 7, 2017
Utilizing metabolomics research techniques, NYU Dentistry researchers investigated the underlying biochemical activity and signaling within the bone marrow of hyperglycemic mice with hopes of reducing fracture risks of diabetics

Immune system killer cells increase risk of diabetes

July 6, 2017
More than half of the German population is obese. One effect of obesity is to chronically activate the immune system, placing it under continuous stress. Researchers in Jens Brüning's team at the Max-Planck-Institute for ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.