Characteristics of long-term gastric cancer survivors ID'd

September 7, 2012
Characteristics of long-term gastric cancer survivors ID'd
Patients with gastric and gastroesophageal junction cancer who survive for longer than three years after diagnosis seem to have distinct demographic and pathologic characteristics, compared with those who do not survive, according to research published online Sept. 4 in the Journal of Clinical Oncology.

(HealthDay)—Patients with gastric and gastroesophageal junction (GEJ) cancer who survive for longer than three years after diagnosis seem to have distinct demographic and pathologic characteristics, compared with those who do not survive, according to research published online Sept. 4 in the Journal of Clinical Oncology.

Pamela L. Kunz, M.D., of the Stanford University School of Medicine in California, and colleagues conducted a population-based study involving 47,647 patients diagnosed with gastric or GEJ adenocarcinoma between 1988 and 2005 who were part of the California Cancer Registry, a member of the 's Surveillance, Epidemiology, and End Results program.

Overall, only 20 percent of patients survived at least three years. The researchers found that longer survival correlated with several factors, including earlier stage, surgery, chemotherapy, radiation, intestinal histology, well- or moderately-differentiated tumors, race (Asian/Pacific Islander and Hispanic), gender (female), socioeconomic status (highest quintile), treatment at an , anatomic location (fundus/body/antrum), and hospital size (more than 150 beds). Patients with tumors originating in the fundus/body/antrum had longer median disease-specific survival compared to those with tumors originating in the esophagus/cardia (13.4 versus 10.8 months). Median disease-specific survival was significantly longer for intestinal histology (28.9 months) compared with other (11.0 months) or diffuse histology (10.1 months).

"This large population-based study will serve as a platform for developing future work to better understand factors involved in long-term survivors of , including genetic, genomic, and survivorship studies," the authors write.

Explore further: Probability of long-term glioblastoma survival assessed

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Probability of long-term glioblastoma survival assessed

May 28, 2012
(HealthDay) -- Although the overall mortality rate of glioblastoma is high, compared with patients newly diagnosed with glioblastoma, those who survive two years or more after diagnosis have a favorable conditional probability ...

Asian lung cancer patient survival exceeds Caucasians' on multiple regimens

June 1, 2011
Asian non-small cell lung cancer (NSCLC) patients survive longer than Caucasians no matter how many drugs are given in a first-line setting, and the effect was apparent both before and after the introduction of targeted therapies ...

Adjuvant radiochemotherapy has lasting benefit in gastric cancer

May 18, 2012
(HealthDay) -- Ten-year data from the Southwestern Oncology Group-directed Intergroup Study 0116 confirm the benefits of adjuvant radiochemotherapy after gastric cancer resection in terms of overall survival (OS) and relapse-free ...

Chemo combo promising for pancreatic neuroendocrine tumors

July 13, 2012
(HealthDay) -- The combination of temozolomide and bevacizumab seems to benefit patients with advanced pancreatic neuroendocrine tumors (NETs), according to a study published online July 9 in the Journal of Clinical Oncology.

Recommended for you

How cancer metastasis happens: Researchers reveal a key mechanism

January 18, 2018
Cancer metastasis, the migration of cells from a primary tumor to form distant tumors in the body, can be triggered by a chronic leakage of DNA within tumor cells, according to a team led by Weill Cornell Medicine and Memorial ...

Modular gene enhancer promotes leukemia and regulates effectiveness of chemotherapy

January 18, 2018
Every day, billions of new blood cells are generated in the bone marrow. The gene Myc is known to play an important role in this process, and is also known to play a role in cancer. Scientists from the German Cancer Research ...

These foods may up your odds for colon cancer

January 18, 2018
(HealthDay)—Chowing down on red meat, white bread and sugar-laden drinks might increase your long-term risk of colon cancer, a new study suggests.

The pill lowers ovarian cancer risk, even for smokers

January 18, 2018
(HealthDay)—It's known that use of the birth control pill is tied to lower odds for ovarian cancer, but new research shows the benefit extends to smokers or women who are obese.

Researchers develop swallowable test to detect pre-cancerous Barrett's esophagus

January 17, 2018
Investigators at Case Western Reserve University School of Medicine and University Hospitals Cleveland Medical Center have developed a simple, swallowable test for early detection of Barrett's esophagus that offers promise ...

Scientists zoom in to watch DNA code being read

January 17, 2018
Scientists have unveiled incredible images of how the DNA code is read and interpreted—revealing new detail about one of the fundamental processes of life.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.