Case study IDs B. miyamotoi as cause of meningoencephalitis

January 17, 2013
Case study IDs <i>B. miyamotoi</i> as cause of meningoencephalitis
The spirochete Borrelia miyamotoi may be an underrecognized cause of meningoencephalitis, according to a case study published in the Jan. 17 issue of the New England Journal of Medicine.

(HealthDay)—The spirochete, Borrelia miyamotoi, may be an underrecognized cause of meningoencephalitis, according to a case study published in the Jan. 17 issue of the New England Journal of Medicine.

Joseph L. Gugliotta, M.D., of the Robert Wood Johnson Medical School in New Brunswick, N.J., and colleagues report the case of a B. miyamotoi infection-associated meningoencephalitis which developed in an immunocompromised patient.

According to the report, an 80-year-old woman who lived on a farm in New Jersey, who had been treated twice for and was immunocompromised due to treatment for non-Hodgkin's lymphoma, developed progressive over a four-month period. She was admitted to the hospital and diagnosed with meningoencephalitis. Although Koch's postulates were not met, the woman's illness was posited to be caused by infection with the spirochete B. miyamotoi as the organism was directly detected in cerebrospinal fluid using both microscopy and assay. Following treatment with antibiotics, the patient's physical and mental conditions improved.

"In older persons, changes in mental status are often attributed to dementia or the aging process. Exposure of such persons to diverse microbial agents, including those thought to be nonpathogenic, such as B. miyamotoi, may represent possibilities for pathologic processes to occur," the authors write. "Immunocompromise in older patients should always prompt a more rigorous laboratory analysis, because such persons may serve as sentinels for poorly recognized or novel pathogens."

Explore further: New tick-borne disease discovered

More information: Full Text (subscription or payment may be required)
Letter to the Editor

Related Stories

New tick-borne disease discovered

September 20, 2011
(Medical Xpress) -- Yale School of Public Health researchers in collaboration with Russian scientists have discovered a new tick-borne bacterium that might be causing disease in the United States and elsewhere. Their findings ...

Deer ticks carry yet another bacterial threat

January 16, 2013
(HealthDay)—People who go outdoors in several regions of the United States may have something else to worry about. Scientists report that there's another troublesome germ hiding in the deer tick that already harbors the ...

Even after Lyme disease is gone, its remains may perpetuate inflammation

June 26, 2012
(Medical Xpress) -- Non-infectious proteins of the species of bacteria that causes Lyme disease can remain in the body for a long time after antibiotic therapy, and are capable of causing an inflammatory immune reaction that ...

Deer tick bacteria DNA in joint fluid not reliable marker of active lyme arthritis

May 17, 2011
New research shows that polymerase chain reaction (PCR) testing for Borrelia burgdorferi DNA—the spirochetal bacteria transmitted by deer ticks—in joint fluid may confirm the diagnosis of Lyme arthritis, but is ...

Recommended for you

Google searches can be used to track dengue in underdeveloped countries

July 20, 2017
An analytical tool that combines Google search data with government-provided clinical data can quickly and accurately track dengue fever in less-developed countries, according to new research published in PLOS Computational ...

MRSA emerged years before methicillin was even discovered

July 19, 2017
Methicillin resistant Staphylococcus aureus (MRSA) emerged long before the introduction of the antibiotic methicillin into clinical practice, according to a study published in the open access journal Genome Biology. It was ...

New test distinguishes Zika from similar viral infections

July 18, 2017
A new test is the best-to-date in differentiating Zika virus infections from infections caused by similar viruses. The antibody-based assay, developed by researchers at UC Berkeley and Humabs BioMed, a private biotechnology ...

'Superbugs' study reveals complex picture of E. coli bloodstream infections

July 18, 2017
The first large-scale genetic study of Escherichia coli (E. coli) cultured from patients with bloodstream infections in England showed that drug resistant 'superbugs' are not always out-competing other strains. Research by ...

Ebola virus can persist in monkeys that survived disease, even after symptoms disappear

July 17, 2017
Ebola virus infection can be detected in rhesus monkeys that survive the disease and no longer show symptoms, according to research published by Army scientists in today's online edition of the journal Nature Microbiology. ...

Mountain gorillas have herpes virus similar to that found in humans

July 13, 2017
Scientists from the University of California, Davis, have detected a herpes virus in wild mountain gorillas that is very similar to the Epstein-Barr virus in humans, according to a study published today in the journal Scientific ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.