Job stress, unhealthy lifestyle increase risk of coronary artery disease

May 13, 2013

People with job stress and an unhealthy lifestyle are at higher risk of coronary artery disease than people who have job stress but lead healthy lifestyles, found a study published in CMAJ (Canadian Medical Association Journal).

To determine whether a can help reduce the effects of job stress on coronary artery disease, researchers looked at 7 cohort studies from a large European initiative that included 102 128 people who were disease-free during the 15-year study period (1985-2000). Participants, ranging in age from 17-70 (mean 44.3) years were from the United Kingdom, France, Belgium, Sweden and Finland. More than half (52%) were women.

Of the total participants, 15 986 (16%) reported job stress, which was determined from specific job-related questions in the studies. The investigators defined three lifestyle categories based on smoking, , physical activity/inactivity and obesity (). A "healthy lifestyle" had no , "moderately unhealthy lifestyle" had one risk factor and "unhealthy lifestyle" included 2-4 lifestyle risk factors.

A total of 1086 participants had incident events of coronary artery disease events during the follow-up period. The 10-year incidence of coronary artery disease was 18.4 per 1000 people for people with job strain and 14.7 for those without job strain. People with an unhealthy lifestyle had a significantly higher 10-year incidence rate (30.6 per 1000) compared to those with a healthy lifestyle (12.0 per 1000). The incidence rate was 31.2 per 1000 for participants with job strain and an unhealthy lifestyle but only 14.7 for those with job strain and a healthy lifestyle.

"The risk of coronary artery disease was highest among participants who reported job strain and an ; those with job strain and a healthy lifestyle had about half the rate of thisdisease," writes Dr. Mika Kivimäki, Department of Epidemiology and Public Health, University College London (UCL), London, United Kingdom. "These observational data suggest that a healthy lifestyle could substantially reduce the risk of risk among people with job strain."

Evidence from randomized controlled trials has shown that lifestyle changes such as weight loss and stopping smoking can reduce the risk of disease.

"In addition to stress counselling, clinicians might consider paying closer attention to lifestyle risk factors in patients who report job strain," the authors conclude.

Explore further: Large Europe-wide study confirms work stress linked to greater risk of heart disease

More information: www.cmaj.ca/lookup/doi/10.1503/cmaj.121735

Related Stories

Large Europe-wide study confirms work stress linked to greater risk of heart disease

September 13, 2012
People who have highly demanding jobs and little freedom to make decisions are 23% more likely to experience a heart attack compared with their counterparts without such work stress, according to a study of nearly 200 000 ...

Healthy lifestyle linked with longer survival among kidney disease patients

March 21, 2013
Certain lifestyle factors—such as not smoking, getting regular physical activity, and avoiding a low body weight—may help prolong the lives of individuals with chronic kidney disease (CKD), according to a study appearing ...

Increased risk of heart attack and death with progressive coronary artery calcium buildup

May 2, 2013
Patients with increasing accumulations of coronary artery calcium were more than six times more likely to suffer from a heart attack or die from heart disease than patients who didn't have increasing accumulations, according ...

Seven simple lifestyle steps may decrease risk of blood clots

May 2, 2013
Blood clots in the legs or lungs (deep vein thrombosis or pulmonary embolism) kill an American about every 5 minutes. Adopting seven simple lifestyle steps could help reduce your risk of these potentially deadly blood clots, ...

Coronary heart disease due to genes, not family lifestyle

August 26, 2011
It has long been known that hereditary factors play a role in coronary heart disease. However, it has been unclear whether the increased risk is transferred through the genes or through an unhealthy lifestyle in the family. ...

Workplace stress poses risk to health

April 23, 2013
Stressful situations at work can have a negative impact on the cardiovascular system and the metabolism. Stress, which is transmitted by direct and indirect signaling pathways, leads to an inflammatory response in the body, ...

Recommended for you

Could aggressive blood pressure treatments lead to kidney damage?

July 18, 2017
Aggressive combination treatments for high blood pressure that are intended to protect the kidneys may actually be damaging the organs, new research from the University of Virginia School of Medicine suggests.

Quantifying effectiveness of treatment for irregular heartbeat

July 17, 2017
In a small proof-of-concept study, researchers at Johns Hopkins report a complex mathematical method to measure electrical communications within the heart can successfully predict the effectiveness of catheter ablation, the ...

Concerns over side effects of statins stopping stroke survivors taking medication

July 17, 2017
Negative media coverage of the side effects associated with taking statins, and patients' own experiences of taking the drugs, are among the reasons cited by stroke survivors and their carers for stopping taking potentially ...

Study discovers anticoagulant drugs are being prescribed against safety advice

July 17, 2017
A study by researchers at the University of Birmingham has shown that GPs are prescribing anticoagulants to patients with an irregular heartbeat against official safety advice.

Protein may protect against heart attack

July 14, 2017
DDK3 could be used as a new therapy to stop the build-up of fatty material inside the arteries

Heart study finds faulty link between biomarkers and clinical outcomes

July 14, 2017
Surrogate endpoints (biomarkers), which are routinely used in clinical research to test new drugs, should not be trusted as the ultimate measure to approve new health interventions in cardiovascular medicine, according to ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.