Registry confirms TAVI efficacy and safety in Asian patients

Transcatheter aortic valve implantation (TAVI) is effective and safe in Asian patients, according to early experience based on first results from a multicentre Asian registry reported at EuroPCR 2013.

"TAVI has become a treatment option for selected patients with symptomatic . But current data are virtually all from North American or European centres," Paul Chiam, senior consultant cardiologist at the National Heart Center, Singapore, told the conference. He explained that it is unknown whether the smaller average physique in Asian patients may affect outcomes after TAVI.

To answer this question, Chiam and colleagues started an investigator-driven registry, collecting data on from patients undergoing TAVI at 14 centres across Asia. These centres are in China, Hong Kong, Malaysia, the Philippines, Singapore, South Korea, Taiwan and Thailand. Patient demographics, clinical characteristics, procedural and 30-day outcomes were recorded and analysed for 253 patients undergoing TAVI between February 2009 and August 2012.

"Procedural success was reported for 97% of undergoing TAVI," said Chiam. Major vascular complications occurred in only 4% of patients by 30 days after their procedure. The 30-day mortality was very low (3%), as was the stroke rate (1.6%). Mean NYHA class at 30 days was 1.4+0.6 and 9% of patients required a permanent pacemaker at this time point. There were no difference in clinical outcomes between the two devices except for significantly more patients requiring a pacemaker after undergoing TAVI with a CoreValve device compared to those where a Sapien device was used (15.7% vs 0.9%, p<0.0001).

Commenting on the implications of the study findings, Chiam concluded, "Early experience suggests that TAVI appears feasible and safe in a physically smaller Asian population, with low stroke and and without an increase in vascular complications."


Explore further

Post-approval TAVI registry shows high rates of device success at one year

Citation: Registry confirms TAVI efficacy and safety in Asian patients (2013, May 24) retrieved 13 October 2019 from https://medicalxpress.com/news/2013-05-registry-tavi-efficacy-safety-asian.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
 shares

Feedback to editors

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more