Pediatric anxiety remission up with acute treatment response

February 3, 2014
Pediatric anxiety remission up with acute treatment response

(HealthDay)—Almost half of youth with anxiety disorders are in remission at six years after randomization to interventions, with those who respond during acute treatment more likely to be in remission, according to a study published online Jan. 29 in JAMA Psychiatry.

Golda S. Ginsburg, Ph.D., from the Johns Hopkins University School of Medicine in Baltimore, and colleagues conducted a naturalistic follow-up study at six academic sites in the United States and involving 288 youth (mean age, 17 years). In the Child/Adolescent Anxiety Multimodal Study (CAMS), participants were randomized to one of four interventions: , medication, combination, or pill placebo.

At a mean of six years after randomization, the researchers found that 46.5 percent of the participants were in remission (absence of all study entry ). Acute treatment responders were more likely to be in remission (odds ratio, 1.83); they also had less severe anxiety symptoms and higher functioning, irrespective of treatment arm assignment. The researchers identified several predictors of remission and functioning.

"Youths rated as responders during the acute treatment phase of CAMS were more likely to be in a mean of six years after , although the effect size was small," the authors write. "Relapse occurred in almost half (48 percent) of acute responders, suggesting the need for more intensive or continued treatment for a sizable proportion of youths with anxiety disorders."

Several authors disclosed financial ties to the pharmaceutical and publishing industries.

Explore further: Less than half of children treated for anxiety achieve long-term relief

More information: Abstract
Full Text (subscription or payment may be required)

Related Stories

Less than half of children treated for anxiety achieve long-term relief

January 29, 2014
Fewer than one in two children and young adults treated for anxiety achieve long-term relief from symptoms, according to the findings of a study by investigators from the Johns Hopkins Children's Center and five other institutions.

Continuation phase cognitive therapy beneficial in depression

September 5, 2013
(HealthDay)—For patients with major depressive disorder, continuation phase cognitive therapy (C-CT) and fluoxetine prevent relapse; and, a cognitive behavioral prevention (CBP) program provides lasting benefits for some ...

Drug improves remission of Crohn disease among children and adolescents

November 26, 2013
Among children and adolescents with Crohn disease not responding to treatment, use of the drug thalidomide resulted in improved clinical remission after 8 weeks of treatment compared with placebo, according to a study appearing ...

Alendronate reduces adjacent-level vertebral fractures

December 30, 2013
(HealthDay)—For females with osteoporosis, the rate of adjacent-level vertebral fractures is relatively low, with reduced odds with bisphosphonate therapy, according to a study published in the Dec. 1 issue of Spine.

High-dose cytarabine improves outcome in patients with AML in EORTC-GIMEMA AML-12 Trial

December 19, 2013
Results of the EORTC and GIMEMA (Gruppo Italiano Malattie Ematologiche dell' Adulto) AML-12 Trial appearing in the Journal of Clinical Oncology show that high-dose cytarabine in induction treatment improves outcome of adult ...

Recommended for you

Short-course treatment for combat-related PTSD offers expedited path to recovery

January 23, 2018
Symptoms of Post-Traumatic Stress Disorder (PTSD) can be debilitating and standard treatment can take months, often leaving those affected unable to work or care for their families. But, a new study demonstrated that many ...

Priming can negate stressful aspects of negative sporting environments, study finds

January 23, 2018
The scene is ubiquitous in sports: A coach yells at players, creating an environment where winning is the sole focus and mistakes are punished. New research from the University of Kansas shows that when participants find ...

Social and emotional skills linked to better student learning

January 23, 2018
Students with well-developed and adaptive social and emotional behaviours are most likely to excel in school, according to UNSW researchers in educational psychology.

Study of learning and memory problems in OCD helps young people unlock potential at school

January 22, 2018
Adolescents with obsessive-compulsive disorder (OCD) have widespread learning and memory problems, according to research published today. The findings have already been used to assist adolescents with OCD obtain the help ...

People with prosthetic arms less affected by common illusion

January 22, 2018
People with prosthetic arms or hands do not experience the "size-weight illusion" as strongly as other people, new research shows.

Intensive behavior therapy no better than conventional support in treating teenagers with antisocial behavior

January 19, 2018
Research led by UCL has found that intensive and costly multisystemic therapy is no better than conventional therapy in treating teenagers with moderate to severe antisocial behaviour.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.