Study links depression to arterial stiffness during stress

March 14, 2014 by Melva Robertson
Study links depression to arterial stiffness during stress
Depressive symptoms significantly increased arterial stiffness induced by mental stress, but had no effect on arterial stiffness with exercise.

(Medical Xpress)—According to a study by researchers at Emory's Rollins School of Public Health, symptoms of depression are associated with an increase in arterial stiffness induced by mental stress. Arterial stiffness indicates a reduced capability of an artery to expand and contract in response to blood pressure change. It is an important indicator of future cardiovascular events and has been shown to worsen during stressful conditions.

The Emory team studied 81 young and middle-aged patients who had a recent heart attack. All subjects underwent an acute emotional stress task in addition to a standard exercise stress test. The researchers measured with a Pulse Wave Velocity system, at rest and 60 minutes after stress, and calculated stress-induced changes in arterial stiffness.

Depressive symptoms significantly increased arterial stiffness induced by , but had no effect on arterial stiffness with exercise. These results were not explained by differences in or heart disease severity.

"Depression may cause worsened arterial stiffness with , but not with exercise," says lead author Pratik Pimple, MBBS, from Emory's Rollins School of Public Health.

"These findings may help explain why depression is linked to adverse cardiovascular outcomes," adds Viola Vaccarino, MD, PhD, the study director and the Wilton Looney Chair of Cardiovascular Research in the Department of Epidemiology at Rollins.

Explore further: A novel method for simultaneously measuring blood pressure and arterial stiffness

Related Stories

A novel method for simultaneously measuring blood pressure and arterial stiffness

February 10, 2012
Arterial stiffness due to is a major contributor to cardiovascular disease but is very difficult to measure. It also can influence blood pressure readings since these rely on the time taken for arteries to return to normal ...

In elderly, hardening of arteries linked to plaques in brain

October 16, 2013
Even for elderly people with no signs of dementia, those with hardening of the arteries are more likely to also have the beta-amyloid plaques in the brain that are a hallmark of Alzheimer's disease, according to a study published ...

Metabolic syndrome linked to arterial stiffness in CKD

June 4, 2012
(HealthDay) -- For patients with chronic kidney disease (CKD), those with metabolic syndrome (MetS) have increased arterial stiffness but no increase in endothelial dysfunction, compared to those without MetS, according to ...

Metabolic disorders predict the hardening of the arterial walls already in childhood

April 25, 2013
Metabolic disorders, such as excess abdominal fat, raised blood pressure, higher levels of insulin, glucose and triglycerides and lower levels of the beneficial HDL cholesterol can be found in children as young as 6 to 8 ...

Arterial stiffness inversely tied to plasma adiponectin levels

September 27, 2012
(HealthDay)—Arterial stiffness is inversely related to plasma adiponectin levels in young, normotensive patients with type 1 diabetes, according to a study published online Sept. 21 in Diabetes Care.

Study finds relationship between dairy food intake and arterial stiffness

June 7, 2012
(Medical Xpress) -- Adults who include dairy foods in their diets might be reducing their arterial stiffness and decreasing their risk of cardiovascular disease, according to a new study by researchers from the University ...

Recommended for you

Could aggressive blood pressure treatments lead to kidney damage?

July 18, 2017
Aggressive combination treatments for high blood pressure that are intended to protect the kidneys may actually be damaging the organs, new research from the University of Virginia School of Medicine suggests.

Quantifying effectiveness of treatment for irregular heartbeat

July 17, 2017
In a small proof-of-concept study, researchers at Johns Hopkins report a complex mathematical method to measure electrical communications within the heart can successfully predict the effectiveness of catheter ablation, the ...

Concerns over side effects of statins stopping stroke survivors taking medication

July 17, 2017
Negative media coverage of the side effects associated with taking statins, and patients' own experiences of taking the drugs, are among the reasons cited by stroke survivors and their carers for stopping taking potentially ...

Study discovers anticoagulant drugs are being prescribed against safety advice

July 17, 2017
A study by researchers at the University of Birmingham has shown that GPs are prescribing anticoagulants to patients with an irregular heartbeat against official safety advice.

Protein may protect against heart attack

July 14, 2017
DDK3 could be used as a new therapy to stop the build-up of fatty material inside the arteries

Heart study finds faulty link between biomarkers and clinical outcomes

July 14, 2017
Surrogate endpoints (biomarkers), which are routinely used in clinical research to test new drugs, should not be trusted as the ultimate measure to approve new health interventions in cardiovascular medicine, according to ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.