Global study to help improve quality of life for patients with diabetes

April 8, 2014
Global study to help improve quality of life for patients with diabetes

Researchers at the Manchester Royal Infirmary's Diabetes Centre and Vascular Surgery Department together with microbiologists from The University of Manchester have recruited the first patient into a global study evaluating the best surgical practice to remove dead tissue from wounds that fail to heal effectively.

The results of the study may lead to changes in clinical care that significantly improve quality of life for patients with diabetes.

Around 2.9 million people in the UK are known to suffer from diabetes, and the condition can lead to a marked loss of feeling in the feet which, coupled with poor circulation, makes the development of foot ulcers relatively common. Ulcers can quite easily become infected and typically take a very long time to heal. In severe cases, the infection can spread to the surrounding bone and joints and become gangrenous, at which point it is necessary to amputate the limb.

To help prevent this circumstance from occurring, patients with diabetes who have infected foot ulcers must be treated quickly and effectively. Traditionally, this would be achieved by surgically removing dead or infected tissue using a scalpel blade, while leaving healthy tissue intact, thus reducing the spread of the infection.

However, this procedure can now be performed using a novel technology known as the WoundWand™ Debridement Device, which preclinical trials suggest may be more effective at reducing bacterial counts. It is hoped this could improve the pace of recovery, thereby helping patients with to recuperate more quickly. The new research study will evaluate the effectiveness of using a WoundWand compared with a scalpel blade to assess the difference in bacterial count, reduction in wound size and improved recovery time.

Chief investigators Drs Frank Bowling and Tawqeer Rashid believe the results of this study could considerably improve the quality of life of patients undergoing these types of procedures, particularly as the improper removal of from is a primary cause of recurring infection, which significantly increases the risk of amputation.

"We are very proud that our team has recruited the first global patient into this important clinical study. By ensuring that patients get the most effective treatment for ulcers, we can improve ," Drs. Bowling & Rashid, based at the Manchester Diabetes Centre and Department of Vascular Surgery respectively, part of Central Manchester University Hospitals NHS Foundation Trust, said.

The WoundWand uses radiofrequency energy to gently and precisely dissolve soft tissue, thereby minimising damage to healthy tissue. The device is a type of Coblation technology, which is already used for wound care, for instance in Sports Medicine, but this will be the first time such techniques have been used to treat diabetic .

Patients taking part in the research, sponsored by creator of the WoundWand ArthroCare, will be treated using either a scalpel or the WoundWand device and will be followed up over 12 weeks to assess the healing of their wound.

Explore further: Tissue repair drug helps heal diabetic foot ulcers

Related Stories

Tissue repair drug helps heal diabetic foot ulcers

February 25, 2014
Patients were twice as likely to have a diabetic foot ulcer heal within eight weeks when they were treated with a tissue repair drug versus a placebo, according to new research accepted for publication in the Endocrine Society's ...

Vibration may help heal chronic wounds

March 31, 2014
Wounds may heal more quickly if exposed to low-intensity vibration, report researchers at the University of Illinois at Chicago.

Researchers use maggots to heal diabetic wounds

September 27, 2011
(Medical Xpress) -- At the recent Interscience Conference on Anti-Microbial Agents and Chemotherapy, Dr. Lawrence Eron from the University of Hawaii presented his results on the use of maggots to heal diabetic wounds. The ...

When it's more than just a flesh wound

March 27, 2014
If you have a sore that hasn't improved in a month then chances are you are not receiving the specialised care you need.

Correct treatment of common diabetic foot infections can reduce amputations

May 22, 2012
Diabetic foot infections are an increasingly common problem, but proper care can save limbs and, ultimately, lives, suggest new guidelines released by the Infectious Diseases Society of America (IDSA).

Factors ID'd in healing failure of diabetic foot ulcers

June 15, 2012
(HealthDay) -- Patients with diabetes whose foot ulcers fail to heal have increased inflammation and aberrant growth factor levels, according to a study published online June 11 in Diabetes.

Recommended for you

Want to win at sports? Take a cue from these mighty mice

July 20, 2017
As student athletes hit training fields this summer to gain the competitive edge, a new study shows how the experiences of a tiny mouse can put them on the path to winning.

A sodium surprise: Engineers find unexpected result during cardiac research

July 20, 2017
Irregular heartbeat—or arrhythmia—can have sudden and often fatal consequences. A biomedical engineering team at Washington University in St. Louis examining molecular behavior in cardiac tissue recently made a surprising ...

Engineered liver tissue expands after transplant

July 19, 2017
Many diseases, including cirrhosis and hepatitis, can lead to liver failure. More than 17,000 Americans suffering from these diseases are now waiting for liver transplants, but significantly fewer livers are available.

Lunatic Fringe gene plays key role in the renewable brain

July 19, 2017
The discovery that the brain can generate new cells - about 700 new neurons each day - has triggered investigations to uncover how this process is regulated. Researchers at Baylor College of Medicine and Jan and Dan Duncan ...

'Smart' robot technology could give stroke rehab a boost

July 19, 2017
Scientists say they have developed a "smart" robotic harness that might make it easier for people to learn to walk again after a stroke or spinal cord injury.

New animal models for hepatitis C could pave the way for a vaccine

July 19, 2017
They say that an ounce of prevention is worth a pound of cure. In the case of hepatitis C—a disease that affects nearly 71 million people worldwide, causing cirrhosis and liver cancer if left untreated—it might be worth ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.