Intensive lifestyle changes lead to lasting improvement in T2DM

June 2, 2014
Intensive lifestyle changes lead to lasting improvement in T2DM

(HealthDay)—For obese/overweight adults with type 2 diabetes, an intensive lifestyle intervention (ILI) is associated with a reduced risk of incident depression and with better physical function, according to a study published in the June issue of Diabetes Care.

Thomas A. Wadden, Ph.D., from the University of Pennsylvania in Philadelphia, and colleagues compared the effects of an ILI with a diabetes support and education (DSE) control intervention on long-term changes in depression symptoms, antidepressant medication use, and health-related quality of life. Participants included 5,145 overweight/obese individuals with who were followed for a median of 9.6 years. They administered the Beck Depression Inventory (BDI) at baseline, annually at years one to four, and at year eight.

The researchers found that, compared with DSE, ILI correlated with a significant reduction in the incidence of mild or greater (BDI scores ≥10; hazard ratio, 0.85; P= 0.0145). Both groups experienced a worsening of Medical Outcome Study Short Form 36 (SF-36) physical component summary scores over time, but throughout the first eight years the ILI reported better physical function than DSE participants (all P values < 0.01). No significant between-group differences were seen in the proportion of participants who used antidepressant medications or in SF-36 mental component summary scores.

"These findings should be considered when evaluating the potential benefits of ILIs," the authors write.

Several authors disclosed financial ties to the pharmaceutical and weight loss industries.

Explore further: Depression, antidepressant use linked to future CVD risk

More information: Abstract
Full Text

Related Stories

Depression, antidepressant use linked to future CVD risk

June 10, 2013
(HealthDay)—For patients with type 2 diabetes, higher self-reported depression symptoms and antidepressant medicine (ADM) use in the previous year are independently associated with developing certain cardiovascular disease ...

Exercise stimulates adiponectin, raises HDL levels

October 18, 2012
(HealthDay)—Intensive lifestyle intervention for weight loss (ILI) significantly improves high-density lipoprotein cholesterol (HDL-C) levels in overweight and obese individuals with type 2 diabetes, which is partially ...

Intensive weight-loss intervention linked with increased chance of partial remission from diabetes

December 18, 2012
Among overweight adults, participation in an intensive lifestyle intervention (that included counseling sessions and targets to reduce caloric intake and increase physical activity) was associated with a greater likelihood ...

Weight loss and increased fitness slow decline of mobility in adults

March 28, 2012
Weight loss and increased physical fitness nearly halved the risk of losing mobility in overweight or obese adults with type 2 diabetes, according to four-year results from the Look AHEAD (Action for Health in Diabetes) trial ...

Depression modifies type A behavior, mortality link in T1DM

August 12, 2013
(HealthDay)—For individuals with type 1 diabetes, type A personality is associated with lower all-cause mortality, with the correlation modified by depressive symptomatology, according to a study published online July 8 ...

Community-based weight loss program aids diabetes management

April 23, 2014
Weight loss and control of blood sugar can reduce the risk of complications in patients with diabetes but this is difficult for many to achieve. A University of California, San Diego School of Medicine randomized controlled ...

Recommended for you

A step closer to a cure for adult-onset diabetes

October 23, 2017
In healthy people, exosomes – tiny structures secreted by cells to allow intercellular communication – prevent clumping of the protein that leads to type 2 diabetes. Exosomes in patients with the disease don't have the ...

Diabetes pill might replace injection to control blood sugar

October 17, 2017
(HealthDay)— An injectable class of diabetes medication—called glucagon-like peptide-1 or GLP-1—might one day be available in pill form, research suggests.

Skimping on sleep may contribute to gestational diabetes

October 17, 2017
The amount of time spent sleeping in the United States has dropped significantly in the past twenty years with almost a quarter of women and 16 percent of men experiencing insufficient sleep. Now, a new study has found that ...

Artificial pancreas performs well in clinical trial

October 16, 2017
During more than 60,000 hours of combined use of a novel artificial pancreas system, participants in a 12-week, multi-site clinical trial showed significant improvements in two key measures of well-being in people living ...

Omega-6 fats may help prevent type 2 diabetes

October 11, 2017
The risk of developing type 2 diabetes could be significantly reduced by eating a diet rich in omega-6 polyunsaturated fats, a new study suggests.

Where there's type 1 diabetes, celiac disease may follow

October 10, 2017
(HealthDay)—Parents of young children with type 1 diabetes need to be on the lookout for symptoms of another autoimmune condition—celiac disease, new research suggests.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.