Research connects pregnancy loss and cardiovascular disease

July 16, 2014

The Annals of Family Medicine published an article detailing research showing that women with a history of pregnancy loss are at higher risk for cardiovascular disease later in adulthood than other women, work completed by physicians in the Center for Primary Care and Prevention (CPCP) at Memorial Hospital of Rhode Island.

The article "Risk of Cardiovascular Disease Among Postmenopausal Women with Prior Pregnancy Loss: The Women's Health Initiative" stems from the analysis of data from the maternity experiences of a sample of 77,701 women, according to Donna Parker, ScD, director for community health and research with the CPCP. Of those, 30.3 percent reported a history of miscarriage, 2.2 percent a history of stillbirth, and 2.2 percent a history of both.

"We found that the adjusted odds for coronary heart disease in women who had one or more stillbirths was 1.27 (95 percent confidence interval (CI), which is a measure of reliability, 1.07-1.51) compared with women who had no stillbirths," Dr. Parker says. "For women with a history of one miscarriage, the odds ratio was 1.19 (95 percent CI, 1.08-1.32). For women with a history of two or more miscarriages, the odds ratio was 1.18 (95 percent CI, 1.04-1.34) compared with no miscarriage."

The researchers found no significant association of ischemic stroke and pregnancy loss, she adds. The association between pregnancy loss and coronary heart disease appeared to be independent of hypertension, , waist-to-hip ratio and white blood cell count.

"These findings contribute to the growing body of evidence that the metabolic, hormonal and hemostatic pathway alterations that are associated with a may contribute to the development of in adulthood," Dr. Parker continues.

Women with a history of or a single stillbirth should be closely monitored and receive early intervention from their primary care physician so risk factors such as diabetes, hypertension, cholesterol, obesity, smoking and diet can be closely monitored and controlled.

Explore further: Many at high cardiovascular risk still not on statins

Related Stories

Many at high cardiovascular risk still not on statins

May 13, 2014
(HealthDay)—Many individuals at high risk for cardiovascular events, such as those with coronary artery disease, diabetes, or both, are not receiving statins, according to research published in the May/June issue of the ...

Sleep-disordered breathing may affect pregnancy outcomes

July 8, 2014
(HealthDay)—Sleep-disordered breathing (SDB) may be associated with adverse pregnancy outcomes, according to research published in the June issue of the American Journal of Obstetrics & Gynecology.

New study into impact on women who lose a baby

June 27, 2013
(Medical Xpress)—Researchers at the University of Adelaide hope that women who experience pregnancy loss - such as miscarriage and stillbirth - will receive better care thanks to new research aimed at finding out exactly ...

Vegetarian black adventists have lower cardiovascular risk

April 21, 2014
(HealthDay)—A vegetarian diet may reduce cardiovascular risk in black individuals, according to research published online March 17 in Public Health Nutrition.

Cesarean section linked to slight increase in future stillbirth and ectopic pregnancy

July 1, 2014
Caesarean section is associated with a slightly increased rate of subsequent stillbirth and ectopic pregnancy, according to a large study of women living in Demark, published in this week in PLOS Medicine. Given the global ...

Blood kisspeptin level test may identify pregnant women at high risk for miscarriage

June 23, 2014
Measuring pregnant women's blood kisspeptin levels early in their pregnancy may effectively predict their risk of miscarriage, a new study finds. The results were presented Saturday at ICE/ENDO 2014, the joint meeting of ...

Recommended for you

Parents have critical role in preventing teen drinking

July 20, 2017
Fewer teenagers are drinking alcohol but more needs to be done to curb the drinking habits of Australian school students, based on the findings of the latest study by Adelaide researchers.

Aging Americans enjoy longer life, better health when avoiding three risky behaviors

July 20, 2017
We've heard it before from our doctors and other health experts: Keep your weight down, don't smoke and cut back on the alcohol if you want to live longer.

Fresh fish oil lowers diabetes risk in rat offspring

July 19, 2017
Fresh fish oil given to overweight pregnant rats prevented their offspring from developing a major diabetes risk factor, Auckland researchers have found.

High-dose vitamin D doesn't appear to reduce the winter sniffles for children

July 18, 2017
Giving children high doses of vitamin D doesn't appear to reduce the winter sniffles, a new study has found.

Scientists develop new supplement that can repair, rejuvenate muscles in older adults

July 18, 2017
Whey protein supplements aren't just for gym buffs according to new research from McMaster university. When taken on a regular basis, a combination of these and other ingredients in a ready-to-drink formula have been found ...

Study: Eating at 'wrong time' affects body weight, circadian rhythms

July 18, 2017
A new high-precision feeding system for lab mice reinforces the idea that the time of day food is eaten is more critical to weight loss than the amount of calories ingested.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.