Effect of maternal glycemia on childhood obesity and metabolic dysfunction

February 2, 2015, Society for Maternal-Fetal Medicine

In a study to be presented on Feb. 5 in an oral concurrent session at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting, in San Diego, researchers will report on the impact of maternal glycemia on childhood obesity and metabolic dysfunction.

The study, titled The Effect of Maternal Glycemia on Childhood Obesity and Metabolic Dysfunction was a secondary analysis of a mild treatment trial long-term follow-up study which looked at the relationship between maternal oral glucose tolerance testing and childhood body mass index, fasting glucose, insulin and anthropometrics in the offspring of untreated mild GDM and non GDM assessed at ages five to 10 years. The study analyzed 236 offspring with untreated mild gestational diabetes mellitus and 481 non GDM. The conclusion was that maternal glycemia is associated with some childhood anthropometric measures of obesity but not with subsequent , fasting glucose or insulin resistance. However, maternal obesity and Hispanic ethnicity were found to be most associated with childhood obesity and .

"We have known for some time that maternal glycemia has a direct impact on neonatal obesity. This analysis confirms that is far more significant as a risk for than are mild elevations of glucose levels during pregnancy.," stated Mark B. Landon, M.D. with the Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network in Bethesda, Md. "This research further suggests that efforts to reduce obesity prior to pregnancy should be emphasized in clinical practice."

Explore further: Pregnancy associated hypertension associated with increased frequency of subsequent hypertension, metabolic syndrome

Related Stories

Pregnancy associated hypertension associated with increased frequency of subsequent hypertension, metabolic syndrome

February 2, 2015
In a study to be presented on Feb. 5 in an oral concurrent session at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting, in San Diego, researchers of the MFMU Network will present findings of ...

Impact of probiotics on metabolic health in women with gestational diabetes

February 2, 2015
In a study to be presented on Feb. 5 in an oral concurrent session at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting, in San Diego, researchers will report on the effect of a probiotic capsule ...

Long-term effect of gestational diabetes treatment uncertain

December 9, 2014
(HealthDay)—The effects of treatment of mild gestational diabetes mellitus (GDM) on long-term child health are unclear, according to research published online Nov. 20 in Diabetes Care.

Gestational diabetes, obesity impact pregnancy outcomes

March 2, 2012
(HealthDay) -- Women with gestational diabetes mellitus (GDM) who are obese have significantly higher odds of adverse pregnancy outcomes, according to findings from the multinational Hyperglycemia and Adverse Pregnancy Outcome ...

Mother's gestational diabetes linked to daughters being overweight later

October 23, 2014
Women who developed gestational diabetes and were overweight before pregnancy were at a higher risk of having daughters who were obese later in childhood, according to new research published today in Diabetes Care.

Maternal insulin resistance changes pancreas, increases metabolic disorders risk in offspring

December 2, 2014
A growing proportion of women of childbearing age are among the estimated one in three Americans who have insulin resistance—a metabolic disorder that can be a precursor to a number of health problems, including diabetes, ...

Recommended for you

Rise in preterm births linked to clinical intervention

January 18, 2018
Research at the University of Adelaide shows preterm births in South Australia have increased by 40 percent over 28 years and early intervention by medical professionals has resulted in the majority of the increase.

New report calls into question effectiveness of pregnancy anti-nausea drug

January 17, 2018
Previously unpublished information from the clinical trial that the U.S. Food and Drug Administration relied on to approve the most commonly prescribed medicine for nausea in pregnancy indicates the drug is not effective, ...

New study finds 'baby brain' is real, but the cause remains mysterious

January 15, 2018
So-called "baby brain" refers to increased forgetfulness, inattention, and mental "fogginess" reported by four out of five pregnant women. These changes in brain function during pregnancy have long been recognised in midwifery ...

Sleep quality improves with help of incontinence drug

January 12, 2018
A drug used to curtail episodes of urinary incontinence in women also improves quality of sleep, a researcher at the Stanford University School of Medicine reports.

Frozen embryos result in just as many live births in IVF

January 10, 2018
Freezing and subsequent transfer of embryos gives infertile couples just as much of a chance of having a child as using fresh embryos for in vitro fertilization (IVF), research from Ho Chi Minh City, Vietnam, and Adelaide, ...

Study suggests air pollution breathed in the months before and after conception increases chance of birth defects

January 8, 2018
A team of researchers with the University of Cincinnati and Cincinnati Children's Hospital has found evidence that indicates that pre-and post-pregnant women living in an area with air pollution are at an increased risk of ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.