Effect of maternal glycemia on childhood obesity and metabolic dysfunction

February 2, 2015

In a study to be presented on Feb. 5 in an oral concurrent session at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting, in San Diego, researchers will report on the impact of maternal glycemia on childhood obesity and metabolic dysfunction.

The study, titled The Effect of Maternal Glycemia on Childhood Obesity and Metabolic Dysfunction was a secondary analysis of a mild treatment trial long-term follow-up study which looked at the relationship between maternal oral glucose tolerance testing and childhood body mass index, fasting glucose, insulin and anthropometrics in the offspring of untreated mild GDM and non GDM assessed at ages five to 10 years. The study analyzed 236 offspring with untreated mild gestational diabetes mellitus and 481 non GDM. The conclusion was that maternal glycemia is associated with some childhood anthropometric measures of obesity but not with subsequent , fasting glucose or insulin resistance. However, maternal obesity and Hispanic ethnicity were found to be most associated with childhood obesity and .

"We have known for some time that maternal glycemia has a direct impact on neonatal obesity. This analysis confirms that is far more significant as a risk for than are mild elevations of glucose levels during pregnancy.," stated Mark B. Landon, M.D. with the Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network in Bethesda, Md. "This research further suggests that efforts to reduce obesity prior to pregnancy should be emphasized in clinical practice."

Explore further: Pregnancy associated hypertension associated with increased frequency of subsequent hypertension, metabolic syndrome

Related Stories

Gestational diabetes, obesity impact pregnancy outcomes

March 2, 2012

(HealthDay) -- Women with gestational diabetes mellitus (GDM) who are obese have significantly higher odds of adverse pregnancy outcomes, according to findings from the multinational Hyperglycemia and Adverse Pregnancy Outcome ...

Recommended for you


Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.