Effect of maternal glycemia on childhood obesity and metabolic dysfunction

February 2, 2015, Society for Maternal-Fetal Medicine

In a study to be presented on Feb. 5 in an oral concurrent session at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting, in San Diego, researchers will report on the impact of maternal glycemia on childhood obesity and metabolic dysfunction.

The study, titled The Effect of Maternal Glycemia on Childhood Obesity and Metabolic Dysfunction was a secondary analysis of a mild treatment trial long-term follow-up study which looked at the relationship between maternal oral glucose tolerance testing and childhood body mass index, fasting glucose, insulin and anthropometrics in the offspring of untreated mild GDM and non GDM assessed at ages five to 10 years. The study analyzed 236 offspring with untreated mild gestational diabetes mellitus and 481 non GDM. The conclusion was that maternal glycemia is associated with some childhood anthropometric measures of obesity but not with subsequent , fasting glucose or insulin resistance. However, maternal obesity and Hispanic ethnicity were found to be most associated with childhood obesity and .

"We have known for some time that maternal glycemia has a direct impact on neonatal obesity. This analysis confirms that is far more significant as a risk for than are mild elevations of glucose levels during pregnancy.," stated Mark B. Landon, M.D. with the Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network in Bethesda, Md. "This research further suggests that efforts to reduce obesity prior to pregnancy should be emphasized in clinical practice."

Explore further: Pregnancy associated hypertension associated with increased frequency of subsequent hypertension, metabolic syndrome

Related Stories

Pregnancy associated hypertension associated with increased frequency of subsequent hypertension, metabolic syndrome

February 2, 2015
In a study to be presented on Feb. 5 in an oral concurrent session at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting, in San Diego, researchers of the MFMU Network will present findings of ...

Impact of probiotics on metabolic health in women with gestational diabetes

February 2, 2015
In a study to be presented on Feb. 5 in an oral concurrent session at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting, in San Diego, researchers will report on the effect of a probiotic capsule ...

Long-term effect of gestational diabetes treatment uncertain

December 9, 2014
(HealthDay)—The effects of treatment of mild gestational diabetes mellitus (GDM) on long-term child health are unclear, according to research published online Nov. 20 in Diabetes Care.

Gestational diabetes, obesity impact pregnancy outcomes

March 2, 2012
(HealthDay) -- Women with gestational diabetes mellitus (GDM) who are obese have significantly higher odds of adverse pregnancy outcomes, according to findings from the multinational Hyperglycemia and Adverse Pregnancy Outcome ...

Mother's gestational diabetes linked to daughters being overweight later

October 23, 2014
Women who developed gestational diabetes and were overweight before pregnancy were at a higher risk of having daughters who were obese later in childhood, according to new research published today in Diabetes Care.

Maternal insulin resistance changes pancreas, increases metabolic disorders risk in offspring

December 2, 2014
A growing proportion of women of childbearing age are among the estimated one in three Americans who have insulin resistance—a metabolic disorder that can be a precursor to a number of health problems, including diabetes, ...

Recommended for you

New study reveals time and day women are most likely to give birth

June 15, 2018
A new study has found that the time and day that women give birth can vary significantly depending on how labour starts and the mode of giving birth.

Blood test for pregnant women can predict premature birth

June 7, 2018
A new blood test for pregnant women detects with 75-80 percent accuracy whether their pregnancies will end in premature birth. The technique can also be used to estimate a fetus's gestational age—or the mother's due date—as ...

Drug combination offers more effective care for patients suffering miscarriage

June 6, 2018
A combination of the drugs mifepristone and misoprostol can help bring closure to some women and their families suffering from miscarriage, and reduces the need for surgical intervention to complete the painful miscarriage ...

Genes, environment and schizophrenia—new study finds the placenta is the missing link

May 28, 2018
Hiding in plain sight, new research shines a spotlight on the placenta's critical role in the nature versus nurture debate and how it confers risk for schizophrenia and likely other neurodevelopmental disorders including ...

Vendors say pot eases morning sickness. Will baby pay a price?

May 22, 2018
(HealthDay)—Nearly 70 percent of Colorado marijuana dispensaries recommended pot products to manage early pregnancy-related morning sickness, new research reveals.

Pregnancy drug DES might have triggered ADHD in the grandchildren of women who used it

May 21, 2018
A study conducted by researchers at Columbia University's Mailman School of Public Health and Harvard T.H. Chan School of Public Health reported elevated odds for attention deficit hyperactivity disorder (ADHD) in the grandchildren ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.