Effect of maternal glycemia on childhood obesity and metabolic dysfunction

In a study to be presented on Feb. 5 in an oral concurrent session at the Society for Maternal-Fetal Medicine's annual meeting, The Pregnancy Meeting, in San Diego, researchers will report on the impact of maternal glycemia on childhood obesity and metabolic dysfunction.

The study, titled The Effect of Maternal Glycemia on Childhood Obesity and Metabolic Dysfunction was a secondary analysis of a mild treatment trial long-term follow-up study which looked at the relationship between maternal oral glucose tolerance testing and childhood body mass index, fasting glucose, insulin and anthropometrics in the offspring of untreated mild GDM and non GDM assessed at ages five to 10 years. The study analyzed 236 offspring with untreated mild gestational diabetes mellitus and 481 non GDM. The conclusion was that maternal glycemia is associated with some childhood anthropometric measures of obesity but not with subsequent , fasting glucose or insulin resistance. However, maternal obesity and Hispanic ethnicity were found to be most associated with childhood obesity and .

"We have known for some time that maternal glycemia has a direct impact on neonatal obesity. This analysis confirms that is far more significant as a risk for than are mild elevations of glucose levels during pregnancy.," stated Mark B. Landon, M.D. with the Eunice Kennedy Shriver National Institute of Child Health and Human Development Maternal-Fetal Medicine Units Network in Bethesda, Md. "This research further suggests that efforts to reduce obesity prior to pregnancy should be emphasized in clinical practice."


Explore further

Pregnancy associated hypertension associated with increased frequency of subsequent hypertension, metabolic syndrome

Provided by Society for Maternal-Fetal Medicine
Citation: Effect of maternal glycemia on childhood obesity and metabolic dysfunction (2015, February 2) retrieved 15 June 2019 from https://medicalxpress.com/news/2015-02-effect-maternal-glycemia-childhood-obesity.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
7 shares

Feedback to editors

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more