More otologic symptoms, hearing loss for HIV-infected

More otologic symptoms, hearing loss for HIV-infected

(HealthDay)—Otologic symptoms and hearing loss are more common among patients with HIV than uninfected controls, according to a study published online March 5 in JAMA Otolaryngology—Head & Neck Surgery.

Jean Valentin F. Fokouo, M.D., from the University of Yaoundé I in Cameroon, and colleagues examined the effect of HIV and highly-active antiretroviral treatment (HAART) on hearing function in a Cameroonian population. Data were included from 90 HIV-positive case patients (30 HART-naive patients, 30 patients receiving first-line HAART, and 30 receiving second-line HAART) and 90 HIV-negative controls. Participants were aged 15 to 49 years, with no history of hearing loss or treatment with a known ototoxic drug.

The researchers found that, compared with HIV-negative patients, HIV-positive patients had more otologic symptoms (41 versus 13; P = 0.04). Hearing loss was seen in 27.2 percent of the HIV-positive group versus 5.6 percent of the HIV-negative group (P = 0.04). The odds of were higher among HIV-infected HAART-naive patients (right ear: odds ratio [OR], 6.7; left ear: OR, 6.2), patients receiving first-line HAART (right ear: OR, 5.6; left ear: OR, 12.5), and receiving second-line HAART (right ear: OR, 6.7; left ear: OR, 3.7), compared with HIV-negative individuals.

"Further studies are needed because controversy remains regarding the factors that lead to ear damage," the authors write.

Explore further

Worse lower, higher, frequency hearing in HIV-positive adults

More information: Abstract
Full Text (subscription or payment may be required)

Copyright © 2015 HealthDay. All rights reserved.

Citation: More otologic symptoms, hearing loss for HIV-infected (2015, March 6) retrieved 18 January 2020 from
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.

Feedback to editors

User comments