Central corneal thickness influenced by body position

Central corneal thickness influenced by body position

(HealthDay)—Central corneal thickness (CCT) is influenced by body position, with a decrease noted in the first 30 minutes of supine positioning, according to a study published online March 14 in Clinical & Experimental Ophthalmology.

Jessica S. Maslin, M.D., from the Yale University School of Medicine in New Haven, Conn., and colleagues conducted a cross-sectional study involving 23 with open-angle and 23 healthy subjects. The authors measured CCT using an ultrasound pachymeter in each subject. Three consecutive measurements were taken in each eye in the sitting position, and in a supine position after 10 and 30 minutes.

The researchers found that CCT decreased with supine positioning at 10 and 30 minutes in healthy subjects (mean = −5.2 µm [P = 0.0043] and −6.5 µm [P < 0.0001], respectively) and in the glaucoma group (mean = −6.7 µm [P = 0.0043] and −10.2 µm [P < 0.0001], respectively). No statistically significant difference was seen between the CCT at 10 and 30 minutes supine in healthy (P = 0.37) and glaucoma patients (P = 0.14). There was a linear decrease in CCT over time (P < 0.0001); there was no significant between-group difference in the slopes (P = 0.40).

"CCT is a dynamic measurement that can be influenced by ," the authors write. "It decreases linearly in the first 30 minutes of supine positioning at a similar rate in both open-angle glaucoma patients and in healthy subjects."


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