Even light-use waterpipe smoking harms the lungs

Even light-use waterpipe smoking harms the lungs
(HealthDay)—Young, light-use waterpipe smokers exhibit a variety of pulmonary abnormalities, according to a study published online March 23 in the American Journal of Respiratory and Critical Care Medicine.

Yael Strulovici-Barel, M.D., from the Weill Cornell Medical College in New York City, and colleagues compared clinical and biological parameters in young, light-use waterpipe-only smokers versus lifelong nonsmokers. Measured parameters included cough and sputum scores, lung function, chest high resolution computed tomography, lung epithelial lining fluid (ELF) metabolome, small airway epithelial (SAE) cell differential and transcriptome, alveolar macrophage (AM) transcriptome, and plasma apoptotic endothelial cell microparticles (EMPs).

Compared to nonsmokers, the researchers found that waterpipe smokers had more cough and sputum. Waterpipe smokers also exhibited lower lung diffusing capacity, abnormal ELF metabolome profile, increased proportions of SAE secretory and intermediate cells, reduced proportions of SAE ciliated and basal cells, markedly abnormal SAE and AM transcriptomes, and elevated levels of apoptotic EMPs, compared to nonsmokers.

"Young, light-use waterpipe-only have a variety of abnormalities in multiple lung-related biologic and clinical parameters, suggesting that even limited waterpipe use has broad consequences on human biology and health," the authors write. "We suggest that large epidemiologic studies should be initiated on the harmful effects of waterpipe smoking."


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Apr 01, 2016
What about just being in Los Angeles or Beijing? Is there some type of scale that we can use? Ex: Hokas can be as bad as 4 hours in LA or Beijing at the highest level smog alert.

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