Review links H. pylori infection with metabolic syndrome

Review links <i>H. pylori</i> infection with metabolic syndrome

(HealthDay)—Helicobacter pylori infection is associated with metabolic syndrome, according to a review and meta-analysis published online June 7 in the Journal of Digestive Diseases.

Sikarin Upala, M.D., from the Bassett Medical Center and Columbia University College of Physicians and Surgeons in Cooperstown, N.Y., and colleagues conducted a systematic review to quantify the effect of H. pylori infection on the risk of metabolic syndrome. A total of 18 trials comprising 27,544 participants met the inclusion criteria; data from six trials were included in the analysis of metabolic syndrome.

The researchers identified a significant correlation between H. pylori and metabolic syndrome, with a pooled odds ratio of 1.34. There were significant differences in fasting blood glucose, high-density lipoprotein cholesterol, body mass index, triglycerides, homeostatic model assessment of insulin resistance, and between the H. pylori-infected and non-infected groups (all P < 0.05).

"Further are required to determine the effect of H. pylori eradication on the improvement of or metabolic markers and to determine the causal relationship," the authors write.

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Citation: Review links H. pylori infection with metabolic syndrome (2016, June 13) retrieved 20 January 2020 from
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