Smoking may have negative effects on sperm quality

smoking
Credit: Vera Kratochvil/public domain

A recent study found that that sperm of men who smoke has a greater extent of DNA damage than that of non-smokers.

Researchers also assessed 422 proteins in participants' sperm. One was absent, 27 proteins were underrepresented, and 6 proteins were over-represented in smokers. Analyses of these proteins suggest that cigarette smoking may promote an in the male reproductive tract.

The BJU International study included 20 nonsmoking men and 20 men who smoked.

"More and more studies are demonstrating a harmful effect of smoking on male fertility. Our results point in the direction of important semen alterations: semen of smokers presents an inflammatory nature, associated with decreased capacity of sperm to achieve fertilization and generate a healthy pregnancy," said Dr. Ricardo Pimenta Bertolla, senior author of the study. "It is especially noteworthy that, in our study, sperm DNA fragmentation was increased. Other studies have proposed this to be a potentially promutagenic effect, which is to say that sperm with altered DNA may lead to health problems in the offspring."


Explore further

Study confirms that sperm quality decreases with age

More information: M. P. Antoniassi et al, Analysis of the sperm functional aspects and seminal plasma proteomic profile from male smokers, BJU International (2016). DOI: 10.1111/bju.13539
Provided by Wiley
Citation: Smoking may have negative effects on sperm quality (2016, June 22) retrieved 20 May 2019 from https://medicalxpress.com/news/2016-06-negative-effects-sperm-quality.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
4 shares

Feedback to editors

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more