Stepwise program can reduce diabetes incidence

Stepwise program can reduce diabetes incidence
(HealthDay)—A culturally-tailored stepwise diabetes prevention program can reduce incidence of diabetes among overweight/obese Asian Indian adults, according to a study published online Aug. 8 in Diabetes Care.

Mary Beth Weber, Ph.D., M.P.H., from Emory University in Atlanta, and colleagues conducted a randomized trial involving 578 overweight/obese Asian Indian adults with isolated impaired glucose tolerance (iIGT), isolated impaired fasting glucose (iIFG), or IFG+IGT. Participants were randomized to standard advice or to a six-month culturally-tailored U.S. Diabetes Prevention Program-based lifestyle curriculum plus addition of metformin for those at highest risk of conversion to .

The researchers found that 34.9 percent of control and 25.7 percent of intervention participants developed diabetes during three years of follow-up (P = 0.014). The relative risk reduction (RRR) was 32 percent; in order to prevent one case of diabetes, the number needed to treat was 9.8. There was variation in RRR by prediabetes type (IFG+IGT, 36 percent; iIGT, 31 percent; and iIFG, 12 percent); participants aged 50 years or older, males, and obese had stronger RRR. In addition to lifestyle, 72 percent of participants also required metformin; however, there was some variability by prediabetes type (iIFG, 76.5 percent; IFG+IGT, 83.0 percent; iIGT, 51.3 percent).

"Stepwise in people with prediabetes can effectively reduce diabetes incidence by a third in community settings; however, people with iIFG may require different interventions," the authors write.

The study was supported by a BRiDGES grant, which was funded by Lilly Diabetes.


Explore further

Selective biomarkers can ID risk of impaired glucose tolerance

More information: Full Text (subscription or payment may be required)

Copyright © 2016 HealthDay. All rights reserved.

Citation: Stepwise program can reduce diabetes incidence (2016, August 12) retrieved 26 March 2019 from https://medicalxpress.com/news/2016-08-stepwise-diabetes-incidence.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
3 shares

Feedback to editors

User comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more