Dietary factors linked to risk of acute pancreatitis

January 30, 2017

(HealthDay)—Dietary factors are associated with pancreatitis, with saturated fat and cholesterol positively linked to gallstone-related acute pancreatitis (AP), according to a study published in the February issue of Clinical Gastroenterology and Hepatology.

Veronica Wendy Setiawan, Ph.D., from the University of Southern California in Los Angeles, and colleagues conducted a prospective analysis of 145,886 African-Americans, Native Hawaiians, Japanese-Americans, Latinos, and whites to characterize dietary factors associated with risk of pancreatitis. Patients were classified as having gallstone-related AP, AP not related to , or recurrent AP or suspected chronic pancreatitis (1,210, 1,222, and 378 patients, respectively).

The researchers observed positive correlations for dietary intakes of saturated fat (P trend = 0.0011) and cholesterol (P trend = 0.0008) and their food sources, including red meat (P trend < 0.0001) and eggs (P trend = 0.0052), with gallstone-related AP. There was an inverse association for fiber intake with gallstone-related AP (P trend = 0.0005) and AP not related to gallstones (P trend = 0.0035). There was an inverse association for vitamin D, mainly from milk, with gallstone-related AP (P trend = 0.0015), while coffee intake was protective for AP not related to gallstones (P < 0.0001). No dietary factors other than were associated with recurrent acute or suspected .

"Dietary fiber protected against AP related and unrelated to gallstones," the authors write. "Coffee drinking protected against AP not associated with gallstones."

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