Risk of endometrial cancer down with intentional weight loss

February 7, 2017

(HealthDay)—Losing weight is associated with a significantly lower risk of endometrial cancer, and that benefit appears to be greatest in obese women, according to a study published online Feb. 6 in the Journal of Clinical Oncology.

The researchers reviewed data from 36,794 American women between the ages of 50 and 79. The study included an average of more than 10 years of follow-up.

Women over 50 who lost 5 percent or more of their had a 29 percent lower risk of endometrial cancer, regardless of their age or how much weight they lost, according to the researchers. Obese women who lost 5 percent or more of their body weight had a 56 percent reduction in their risk. Overweight or who achieved a normal body mass index (BMI) had the same risk as women who maintained a normal BMI. The researchers also found that women who gained more than 10 pounds had a 26 percent increased risk of .

"Many think it's too late to benefit from weight loss, or think that because they are overweight or obese, the damage has already been done. But our findings show that's not true," study author Juhua Luo, Ph.D., an associate professor of epidemiology and biostatistics at the Indiana University Bloomington School of Public Health, said a news release from the American Society of Clinical Oncology. "It's never too late, and even moderate weight loss can make a big difference when it comes to cancer risk."

Explore further: Significant weight gain in adulthood increased risk for endometrial cancer

More information: Full Text
Editorial

Related Stories

Significant weight gain in adulthood increased risk for endometrial cancer

October 24, 2011
Postmenopausal women who gained weight during adulthood had an increased risk for endometrial cancer compared with women who maintained a stable weight, according to data from the American Cancer Society's Cancer Prevention ...

Study explores link between weight and stroke risk in women

September 8, 2016
(HealthDay)—Excess weight may put women at increased risk for ischemic stroke, but at lower risk for hemorrhagic stroke, according to research published online Sept. 7 in Neurology.

Inadequate weight gain in overweight moms tied to SGA

August 5, 2014
(HealthDay)—For overweight and obese women, inadequate weight gain is associated with increased risk of small for gestational age (SGA), according to a study published in the August issue of the America Journal of Obstetrics ...

Cluster of heart risk factors tied to uterine cancer risk

January 13, 2015
(HealthDay)—A collection of health risk factors known as the "metabolic syndrome" may boost older women's risk of endometrial cancer, even if they're not overweight or obese, a new study suggests.

Less chemo for obese ovarian cancer patients linked to worse survival rates

July 6, 2015
(HealthDay)—Ovarian cancer patients who are overweight or obese are often given lower doses of chemotherapy per pound of body weight, but this may reduce the odds of survival, a new study suggests.

New study links obesity, starting at adolescence, to endometrial cancer among women not using hormone therapy

November 11, 2016
While it is well established that obesity is closely linked to endometrial cancer risk, most past findings have only looked at risk in relation to one measure of body size at a time. In this study led by the Cancer Prevention ...

Recommended for you

Fully reprogrammed virus offers new hope as cancer treatment

May 25, 2018
A cancer treatment that can completely destroy cancer cells without affecting healthy cells could soon be a possibility, thanks to research led by Cardiff University.

Research could help fine-tune cancer treatment

May 25, 2018
Cancer therapies that cut off blood supply to a tumour could be more effective in combination with existing chemotherapeutic drugs—according to new research from the University of East Anglia.

Increasing physical activity linked to better immunity in breast cancer patients, study finds

May 25, 2018
A new study from the University of Toronto's Faculty of Kinesiology & Physical Education has found that moderate to vigorous physical activity may help regulate the levels of C-reactive protein – an important biomarker ...

Low-fat diet tied to better breast cancer survival

May 24, 2018
(HealthDay)—Breast cancer patients who adopted a low-fat diet were more likely to survive for at least a decade after diagnosis, compared to patients who ate fattier fare, new research shows.

A cascade of immune processes offers insights to triple-negative breast cancer

May 24, 2018
Cancer is crafty. To survive and thrive, tumors find a way of thwarting our body's natural systems.

By forming clots in tumors, immune cell aids lung cancer's spread

May 24, 2018
University of North Carolina Lineberger Comprehensive Cancer Center researchers have found that by helping to form clots within tumors, immune cells that flock to a particular type of lung cancer are actually building a foundation ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.