Risk of endometrial cancer down with intentional weight loss

February 7, 2017

(HealthDay)—Losing weight is associated with a significantly lower risk of endometrial cancer, and that benefit appears to be greatest in obese women, according to a study published online Feb. 6 in the Journal of Clinical Oncology.

The researchers reviewed data from 36,794 American women between the ages of 50 and 79. The study included an average of more than 10 years of follow-up.

Women over 50 who lost 5 percent or more of their had a 29 percent lower risk of endometrial cancer, regardless of their age or how much weight they lost, according to the researchers. Obese women who lost 5 percent or more of their body weight had a 56 percent reduction in their risk. Overweight or who achieved a normal body mass index (BMI) had the same risk as women who maintained a normal BMI. The researchers also found that women who gained more than 10 pounds had a 26 percent increased risk of .

"Many think it's too late to benefit from weight loss, or think that because they are overweight or obese, the damage has already been done. But our findings show that's not true," study author Juhua Luo, Ph.D., an associate professor of epidemiology and biostatistics at the Indiana University Bloomington School of Public Health, said a news release from the American Society of Clinical Oncology. "It's never too late, and even moderate weight loss can make a big difference when it comes to cancer risk."

Explore further: Significant weight gain in adulthood increased risk for endometrial cancer

More information: Full Text
Editorial

Related Stories

Significant weight gain in adulthood increased risk for endometrial cancer

October 24, 2011
Postmenopausal women who gained weight during adulthood had an increased risk for endometrial cancer compared with women who maintained a stable weight, according to data from the American Cancer Society's Cancer Prevention ...

Study explores link between weight and stroke risk in women

September 8, 2016
(HealthDay)—Excess weight may put women at increased risk for ischemic stroke, but at lower risk for hemorrhagic stroke, according to research published online Sept. 7 in Neurology.

Inadequate weight gain in overweight moms tied to SGA

August 5, 2014
(HealthDay)—For overweight and obese women, inadequate weight gain is associated with increased risk of small for gestational age (SGA), according to a study published in the August issue of the America Journal of Obstetrics ...

Cluster of heart risk factors tied to uterine cancer risk

January 13, 2015
(HealthDay)—A collection of health risk factors known as the "metabolic syndrome" may boost older women's risk of endometrial cancer, even if they're not overweight or obese, a new study suggests.

Less chemo for obese ovarian cancer patients linked to worse survival rates

July 6, 2015
(HealthDay)—Ovarian cancer patients who are overweight or obese are often given lower doses of chemotherapy per pound of body weight, but this may reduce the odds of survival, a new study suggests.

New study links obesity, starting at adolescence, to endometrial cancer among women not using hormone therapy

November 11, 2016
While it is well established that obesity is closely linked to endometrial cancer risk, most past findings have only looked at risk in relation to one measure of body size at a time. In this study led by the Cancer Prevention ...

Recommended for you

Outdoor light at night linked with increased breast cancer risk in women

August 17, 2017
Women who live in areas with higher levels of outdoor light at night may be at higher risk for breast cancer than those living in areas with lower levels, according to a large long-term study from Harvard T.H. Chan School ...

Scientists develop novel immunotherapy technology for prostate cancer

August 17, 2017
A study led by scientists at The Wistar Institute describes a novel immunotherapeutic strategy for the treatment of cancer based on the use of synthetic DNA to directly encode protective antibodies against a cancer specific ...

Scientists develop blood test that spots tumor-derived DNA in people with early-stage cancers

August 16, 2017
In a bid to detect cancers early and in a noninvasive way, scientists at the Johns Hopkins Kimmel Cancer Center report they have developed a test that spots tiny amounts of cancer-specific DNA in blood and have used it to ...

Toxic formaldehyde is produced inside our own cells, scientists discover

August 16, 2017
New research has revealed that some of the toxin formaldehyde in our bodies does not come from our environment - it is a by-product of an essential reaction inside our own cells. This could provide new targets for developing ...

Cell cycle-blocking drugs can shrink tumors by enlisting immune system in attack on cancer

August 16, 2017
In the brief time that drugs known as CDK4/6 inhibitors have been approved for the treatment of metastatic breast cancer, doctors have made a startling observation: in certain patients, the drugs—designed to halt cancer ...

Researchers find 'switch' that turns on immune cells' tumor-killing ability

August 16, 2017
Molecular biologists led by Leonid Pobezinsky and his wife and research collaborator Elena Pobezinskaya at the University of Massachusetts Amherst have published results that for the first time show how a microRNA molecule ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.