Mother-to-child HIV transmission low, but more progress possible

March 13, 2017

(HealthDay)—A small proportion of HIV-infected women continue to transmit the virus to their neonates despite access to high-quality care, according to research published in the April issue of Obstetrics & Gynecology.

Gwendolyn B. Scott, M.D., from the University of Miami Miller School of Medicine, and colleagues examined data relating to HIV-infected children born from 2002 to 2009 to HIV-infected . The authors describe the characteristics of the HIV-infected infants and their mothers, as well as mother's clinical management.

The researchers identified 12 cases of mother-to-child HIV transmission among 1,857 liveborn (prevalence, 0.65 per 100 live births to HIV-infected women). Transmission was in utero for four neonates, peripartum for three neonates, and unable to be determined for five neonates. None of the infants were breastfed. Near delivery, seven of the women had plasma >400 copies/mL. During pregnancy, six women had less than 11 weeks of antiretroviral therapy; three of these women had premature deliveries. One woman was diagnosed with HIV postpartum and received no antiretroviral therapy during pregnancy. Poor-to-moderate adherence to was reported for six mothers. Preterm delivery occurred in four of five mothers with viral loads >1,000 copies/mL. Five women were delivered by cesarean, including four non-elective cesarean deliveries.

"This case series provides insight into factors contributing to HIV perinatal transmission and can inform the development of new strategies for prevention of mother-to-child transmission of HIV," the authors write.

Explore further: Mother-child HIV transmission at all time low in U.K. and Ireland

More information: Abstract/Full Text (subscription or payment may be required)

Related Stories

Mother-child HIV transmission at all time low in U.K. and Ireland

December 8, 2016
The number of mothers passing the HIV virus to their babies has fallen to a new record low in the UK and Ireland thanks to the very high take-up of antenatal HIV screening and treatment which reduces virus levels in the pregnant ...

Prophylaxis strategy prevents perinatal HBV transmission

May 28, 2014
(HealthDay)—Prenatal screening followed by immunoprophylaxis for infants of mothers with chronic hepatitis B virus (HBV) infection decreases perinatal transmission, according to research published online May 27 in the Annals ...

Hospitalizations in pregnancy, delivery stable for HIV-infected

October 10, 2016
(HealthDay)—From 2004 to 2011 there was no increase in the number of hospitalizations during pregnancy and delivery for HIV-infected women, according to a study published in the October issue of the American Journal of ...

Scientists call for new strategy in pursuit of HIV-free generation

July 30, 2014
In light of the recent news that HIV has been detected in the Mississippi baby previously thought to have been cured of the disease, researchers are assessing how to help those born to HIV-infected mothers. These infants ...

Drug combo much better than AZT alone at preventing mother-to-infant HIV transmission

June 20, 2012
Non-breastfed babies born to HIV-positive mothers who didn't receive antiretroviral therapy during pregnancy are routinely given zidovudine, commonly known as AZT, shortly after birth to prevent mother-to-child transmission ...

HIV therapy for breastfeeding mothers can virtually eliminate transmission to babies

July 18, 2016
For HIV-infected mothers whose immune system is in good health, taking a three-drug antiretroviral regimen during breastfeeding essentially eliminates HIV transmission by breast milk to their infants, according to results ...

Recommended for you

Pregnancy drug DES might have triggered ADHD in the grandchildren of women who used it

May 21, 2018
A study conducted by researchers at Columbia University's Mailman School of Public Health and Harvard T.H. Chan School of Public Health reported elevated odds for attention deficit hyperactivity disorder (ADHD) in the grandchildren ...

Male depression may lower pregnancy chances among infertile couples, study suggests

May 17, 2018
Among couples being treated for infertility, depression in the male partner was linked to lower pregnancy chances, while depression in the female partner was not found to influence the rate of live birth, according to a study ...

Fertility study finds acupuncture ineffective for IVF birth rates

May 15, 2018
A study of over 800 Australian and New Zealand women undergoing acupuncture treatment during their IVF (in vitro fertilization) cycle has confirmed no significant difference in live birth rates. The findings published today ...

More than one day of first-trimester bleeding ups odds for smaller baby

May 10, 2018
(HealthDay)—Some first-trimester bleeding occurs in up to 1 in every 4 pregnancies. Now, new research suggests that if bleeding extends beyond a day there could be implications for baby's birth weight.

For women with history of pregnancy loss, walking may aid chance of becoming pregnant

May 8, 2018
Results of a recent study to better understand modifiable factors such as physical activity that may affect a woman's ability to conceive a child suggest that walking may help women to improve their chances of becoming pregnant.

Women who eat fast food take longer to become pregnant

May 3, 2018
Women who eat less fruit and more fast food take longer to get pregnant and are less likely to conceive within a year, according to a study by researchers at the University of Adelaide's Robinson Research Institute.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.