Six variables can predict mortality risk in cardiogenic shock

April 14, 2017

(HealthDay)—Six variables can be combined to predict short-term mortality risk in patients with cardiogenic shock (CS), according to a study published in the April 18 issue of the Journal of the American College of Cardiology.

Janine Pöss, M.D., from the University Heart Center in Lübeck, Germany, and colleagues developed a risk prediction score for short-term mortality in with CS after acute , derived from the Intraaortic Balloon Pump in Cardiogenic Shock (IABP-SHOCK II) trial.

The researchers found that age >73 years, prior stroke, glucose at admission >10.6 mmol/L, creatinine at admission >132.6 µmol/L, Thrombolysis In Myocardial Infarction flow grade <3 after percutaneous coronary intervention, and arterial blood lactate at admissions >5 mmol/L were independent predictors of 30-day mortality and were used as parameters. The observed 30-day mortality rates for low, intermediate, and high risk score categories were 23.8, 49.2, and 76.6 percent, respectively (P < 0.0001). Good discrimination was seen on validation in the IABP-SHOCK II registry, with an area under the curve of 0.79. In the CardShock trial external validation population, short-term mortality rates were 28.0, 42.9, and 77.3 percent, respectively (P < 0.001), with an area under the curve of 0.73.

"The IABP-SHOCK II risk score can be easily calculated in daily clinical practice and strongly correlated with mortality in patients with infarct-related CS," the authors write. "It may help stratify patient risk for short-term and might, thus, facilitate clinical decision making."

The study was partially funded by Maquet Cardiopulmonary and Teleflex Medical.

Explore further: Patient-level model predicts in-hospital mortality in acute MI

More information: Abstract/Full Text (subscription or payment may be required)
Editorial (subscription or payment may be required)

Related Stories

Patient-level model predicts in-hospital mortality in acute MI

August 4, 2016
(HealthDay)—A parsimonious patient-level clinical risk model can predict in-hospital mortality for patients with acute myocardial infarction, according to a study published in the Aug. 9 issue of the Journal of the American ...

Intraaortic balloon pump fails to improve mortality rate in cardiogenic shock patients: The IABP-SHOCK II study

August 27, 2012
A balloon pump inserted in the aorta is currently the most widely used support device in the treatment of cardiogenic shock and, since its introduction in 1968, has been used in several million people. However, there is still ...

Increase in use of mechanical circulatory support in PCI

December 23, 2015
(HealthDay)—For patients undergoing percutaneous coronary intervention (PCI) there has been an increase in use of mechanical circulatory support (MCS), according to a study published in the Jan. 1 issue of The American ...

Age, creatinine, ejection fraction predict post-MI survival

April 20, 2015
(HealthDay)—A simple age, creatinine, and ejection fraction (ACEF) score can predict one-year mortality risk in myocardial infarction 30-day survivors who underwent percutaneous coronary intervention, according to a study ...

Long-term thrombolytic Tx no benefit in intermediate-risk PE

March 27, 2017
(HealthDay)—Among patients with intermediate- to high-risk pulmonary embolism (PE), thrombolytic treatment with tenecteplase does not affect long-term mortality rates or rates of other complications, according to a study ...

Quick SOFA score predicts in-hospital mortality risk

January 19, 2017
(HealthDay)—For patients with suspected infection presenting to the emergency department, the quick Sequential Organ Failure Assessment (qSOFA) score is better than systemic inflammatory response syndrome (SIRS) or severe ...

Recommended for you

No sweat required: Team finds hypertension treatment that mimics effect of exercise

October 16, 2018
Couch potatoes rejoice—there might be a way to get the blood pressure lowering benefits of exercise in pill form.

New model suggests cuffless, non-invasive blood pressure monitoring possible using pulse waves

October 16, 2018
A large team of researchers from several institutions in China and the U.S. has developed a model that suggests it should be possible to create a cuffless, non-invasive blood pressure monitor based on measuring pulse waves. ...

Why heart contractions are weaker in those with hypertrophic cardiomyopathy

October 16, 2018
When a young athlete suddenly dies of a heart attack, chances are high that they suffer from familial hypertrophic cardiomyopathy (HCM). Itis the most common genetic heart disease in the US and affects an estimated 1 in 500 ...

Novel genetic study sheds new light on risk of heart attack

October 12, 2018
Loss of a protein that regulates mitochondrial function can greatly increase the risk of myocardial infarction (heart attack), Vanderbilt scientists reported Oct. 3 in the journal eLife.

Researchers say ritual for orthodox Jewish men may offer heart benefits

October 11, 2018
A pilot study led by researchers at the University of Cincinnati (UC) College of Medicine suggests Jewish men who practice wearing tefillin, which involves the tight wrapping of an arm with leather banding as part of daily ...

Markers of dairy fat consumption linked to lower risk of type two diabetes

October 10, 2018
Higher levels of biomarkers of dairy fat consumption are associated with a lower risk of developing type 2 diabetes, according to new research published today in PLOS Medicine. The study, in more than 60,000 adults, was undertaken ...


Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.