PTSD linked with increased lupus risk

September 20, 2017, Wiley
PTSD
Regions of the brain associated with stress and posttraumatic stress disorder. Credit: National Institutes of Health

In a study published in Arthritis & Rheumatology, trauma exposure and posttraumatic stress disorder (PTSD) in civilian women were strongly associated with increased risk of developing lupus, an autoimmune disease.

In the study of 54,763 women, investigators found a nearly three-fold elevated risk of lupus among women with probable PTSD and more than two-fold higher risk of lupus among women who had experienced any traumatic event compared with women not exposed to trauma.

The findings contribute to growing evidence that psychosocial trauma and associated stress responses may lead to autoimmune disease.

"We were surprised that exposure to trauma was so strongly associated with risk of lupus—trauma was a stronger predictor of developing than smoking," said Dr. Andrea Roberts, lead author of the study. Our results add to considerable scientific evidence that our mental health substantially affects our physical health, making access to even more urgent."

Lupus Awareness Month takes place during October in the UK every year.

Explore further: Reports reveal racial and ethnic disparities in lupus rates

More information: Arthritis & Rheumatology, DOI: 10.1002/art.40222

Related Stories

Reports reveal racial and ethnic disparities in lupus rates

September 11, 2017
Two new papers reveal striking racial and ethnic disparities in the incidence and prevalence of lupus, a systemic autoimmune disease that can affect virtually any organ system. The reports, which are published in Arthritis ...

New study reveals hidden burden of Lupus among Hispanic and Asian women in Manhattan

September 11, 2017
Within Manhattan's diverse population, the chronic and often debilitating autoimmune disease lupus affects Hispanic and Asian women more frequently than white women, according to a new study led by investigators at NYU School ...

Exercise may stem kidney damage in lupus patients

September 19, 2017
(HealthDay)—Regular exercise may slow kidney damage in people with lupus while stress may prompt the opposite effect, new research suggests.

New blood test detects stroke and heart attack risk in lupus patients with no CVD symptoms

June 15, 2017
The results of a study presented today at the Annual European Congress of Rheumatology (EULAR) 2017 press conference have shown that a specific biomarker detected in the blood of lupus patients with no symptoms of cardiovascular ...

Lupus may contribute to pregnancy-related complications

February 1, 2016
A new study found that lupus during pregnancy may have negative health impacts for women and their babies. The study included 13,598 Swedish women in their first pregnancy, and all were singleton pregnancies. Preeclampsia, ...

PTSD symptomatology linked to increased risk of RA

March 9, 2016
(HealthDay)—Posttraumatic stress disorder (PTSD) symptomatology is associated with the risk of rheumatoid arthritis (RA) in women, according to a study published in the March issue of Arthritis Care & Research.

Recommended for you

How the brain plays a role in rheumatoid arthritis inflammation

June 18, 2018
In patients with chronic inflammatory conditions, such as rheumatoid arthritis, there has been limited understanding of how this inflammation affects the brain.

New 3-D imaging analysis technique could lead to improved arthritis treatment

June 18, 2018
An algorithm to monitor the joints of patients with arthritis, which could change the way that the severity of the condition is assessed, has been developed by a team of engineers, physicians and radiologists led by the University ...

Joint resolution: A link between Huntington's disease and rheumatoid arthritis

May 15, 2018
Using new analytic tools, researchers at University of California San Diego School of Medicine and the Icahn School of Medicine at Mount Sinai have decoded the epigenetic landscape for rheumatoid arthritis (RA), a common ...

Get off the golf cart if you have knee osteoarthritis

April 28, 2018
From presidents to retirees, more than 17 million people over the age of 50 golf regularly. Knee osteoarthritis, which causes swelling, pain and difficulty moving the joint, is one of the leading causes of disability in this ...

How environmental pollutants and genetics work together in rheumatoid arthritis

April 19, 2018
It has been known for more than three decades that individuals with a particular version of a gene—human leukocyte antigen (HLA)—have an increased risk for rheumatoid arthritis.

The bugs in your gut could make you weak in the knees

April 19, 2018
Bacteria in the gut, known as the gut microbiome, could be the culprit behind arthritis and joint pain that plagues people who are obese, according to a new study published today in JCI Insight.

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.