Patients use about half of opioids prescribed after hysterectomy

November 10, 2017

(HealthDay)—Gynecologists prescribe about twice the amount of opioids than patients use after hysterectomy for benign, nonobstetric indications, according to a study published online Nov. 7 in Obstetrics & Gynecology.

Sawsan As-Sanie, M.D., M.P.H., from the University of Michigan in Ann Arbor, and colleagues quantified physician prescribing patterns and patient use in the two weeks after for benign, nonobstetric indications. Patients completed the Fibromyalgia Survey before hysterectomy, and opioid use and were obtained after surgery. One hundred two participated (43.1 percent underwent laparoscopic, 41.2 percent vaginal, and 15.7 percent abdominal hysterectomies).

The researchers found that 200 oral morphine equivalents was the median amount of opioids prescribed. Patients reported using about half of the opioids prescribed, with a median excess of 110 oral morphine equivalents. Preoperative Fibromyalgia Survey score, overall body pain, preoperative opioid use, prior endometriosis, abdominal (versus laparoscopic) hysterectomy, and uterine weight were significant predictors in the best fit model of total opioid consumption. There was a correlation for highest tertile of Fibromyalgia Survey score with greater daily opioid consumption (13.9 greater oral morphine equivalents at baseline).

"A personalized approach to prescribing opioids for postoperative pain should be considered," the authors write.

Several authors disclosed financial ties to the pharmaceutical industry.

Explore further: Opioids often overprescribed in patients undergoing surgery

More information: Abstract/Full Text (subscription or payment may be required)

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