Gene twist can make your blood pressure spike from salt

April 18, 2018

(HealthDay)—New research sheds light on why some people's blood pressure is especially sensitive to salt.

The research team previously discovered that a natural gene variation that occurs in 48 percent of people increases a person's chances of having that's sensitive to salt. Their new study revealed how this gene variant prevents the body from eliminating excess salt.

The gene variant causes a sodium (salt) transporter called NBCe2 to overwork, bringing too much sodium filtered in the kidney back into the body, particularly after a high-salt meal. That means that consuming too much salt could be especially dangerous for people with this .

Blood pressure that's sensitive to salt can be difficult to diagnose and treat, according to the researchers, because about 14 percent of people can have and still be salt-sensitive.

About three out of 10 people are sensitive to salt and their inability to eliminate excess puts them at increased risk of heart attack, stroke, and blindness, according to study senior author Robin Felder, from the department of pathology at the University of Virginia School of Medicine, and colleagues.

"It's important for the body to get rid of excess sodium because having too much sodium in the body causes the body to retain water, which can raise blood pressure and significantly shorten one's lifespan," Felder said in a university news release.

The study was published online recently in the journal PLOS One.

Explore further: Quinn on Nutrition: Sodium: How low can we go?

More information: The American Heart Association has more on salt.

Related Stories

Quinn on Nutrition: Sodium: How low can we go?

March 2, 2018
As with much of this science of nutrition, experts don't always agree on what's best for us. Not that they don't have good information. Sometimes we have lots of valid data. But Mr. Jones' response to a dietary change may ...

Salt, inflammation and hypertension

November 14, 2017
Although dietary salt intake positively correlates with blood pressure, the mechanisms linking salt to hypertension are not well understood.

Chinese takeout has so much salt it should carry a 'health warning,' UK advocacy group says

March 16, 2018
A UK advocacy group has added a little extra salt to sodium's existing wounds.

Healthy diet may not offset high salt intake

March 5, 2018
A healthy diet may not offset the effects of a high salt intake on blood pressure, suggests a new study.

Spicy food may curb unhealthy cravings for salt

October 31, 2017
Chinese subjects who enjoyed spicy foods appeared to eat less salt and have lower blood pressure, potentially reducing their risk of heart attack and stroke, according to new research in the American Heart Association's journal ...

Recommended for you

Study reveals new link between atrial fibrillation and mutations in heart disease gene

December 11, 2018
Atrial fibrillation (Afib), a heart condition that causes a rapid, irregular heartbeat that increases a person's risk of stroke and heart failure, is fairly common among older adults. However, its early onset form is relatively ...

Researchers have found that incidence of heart failure was around two-fold higher in people with diabetes

December 11, 2018
Researchers have found that incidence of heart failure was around two-fold higher in people with diabetes.

Study: Age, race differences determine risk of stroke in women and men

December 11, 2018
A new study found that, between the ages of 45 and 74 years, white women were less likely to have a stroke than white men, but at age 75 and older, there was no difference in stroke risk between white women and men. In contrast, ...

Research team traces pathway to cardioprotection in post-ischemic heart failure

December 11, 2018
During an ischemic attack, the heart is temporarily robbed of its blood supply. The aftermath is devastating: reduced heart contractility, heart cell death, and heart failure. Contributing to these detrimental changes is ...

Possible connection between cardiovascular disease and living near oil and gas wells

December 11, 2018
Researchers at the Colorado School of Public Health have found a possible connection between the intensity of oil and gas exploration in an area and early indicators of cardiovascular disease among nearby residents.

Study links frequent red meat consumption to high levels of chemical associated with heart disease

December 11, 2018
Researchers have identified another reason to limit red meat consumption: high levels of a gut-generated chemical called trimethylamine N-oxide (TMAO), that also is linked to heart disease. Scientists found that people who ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.