One-hour plasma glucose useful predictor of diabetic retinopathy

April 16, 2018

(HealthDay)—One- and two-hour plasma glucose concentrations (1h-PG and 2h-PG, respectively) are similarly effective at predicting diabetic retinopathy (DR), according to a study published online April 5 in Diabetes Care.

Ethan Paddock, from the National Institutes of Health in Phoenix, and colleagues assessed the ability of 1h-PG and 2h-PG, derived from a 75-g test (OGTT), to predict DR among an American Indian community in the southwestern United States. The authors assessed cross-sectional and longitudinal cohorts of 2,895 and 1,703 individuals, respectively.

The researchers found that the prevalence and incidence of DR changed in a similar manner across the distributions of 1h-PG and 2h-PG concentrations. Overall, 1h-PG and 2h-PG showed similar value in identifying prevalent and incident DR using direct ophthalmoscopy. The cut points of 230 (type 2 diabetes) and 173 mg/dL (impaired glucose tolerance) in the 1h-PG were comparable to 2h-PG cut points of 200 mg/dL and 140 mg/dL, respectively.

"1h-PG is a useful predictor of retinopathy risk, has a predictive value similar to that of 2h-PG, and may be considered as an alternative time point during an OGTT," the authors write.

Explore further: Similar defects ID'd for T2DM, chronic pancreatitis and diabetes

More information: Abstract/Full Text (subscription or payment may be required)

Related Stories

Similar defects ID'd for T2DM, chronic pancreatitis and diabetes

August 2, 2017
(HealthDay)—Patients with type 2 diabetes and those with diabetes secondary to chronic pancreatitis have similarly impaired α-cell responses to oral glucose ingestion and hypoglycemia, according to a study published online ...

Progression of dysglycemia in youth similar to adults

July 12, 2014
(HealthDay)—For obese adolescents, glucose sensitivity deteriorates progressively across the spectrum of glucose tolerance, according to a study published online June 19 in Diabetes.

Children at risk of diabetes should be screened by HbA1C, oral glucose tolerance tests

April 4, 2017
Doctors should add an oral glucose tolerance test (OGTT) to their hemoglobin A1C (HbA1C) when they screen high-risk children for prediabetes and diabetes, new research from South Korea suggests. The study results will be ...

Selective biomarkers can ID risk of impaired glucose tolerance

April 8, 2016
(HealthDay)—Selective biomarkers can identify the risk of isolated impaired glucose tolerance (iIGT), according to a study published online April 5 in Diabetes Care.

Tooth health may indicate diabetes risk

March 19, 2018
Poor dental health may be linked with increased risk for diabetes, a new study suggests. The results will be presented in a poster Monday, March 19, at ENDO 2018, the 100th annual meeting of the Endocrine Society in Chicago, ...

4.4 mmol/L is optimal fasting glucose cutoff for GDM screening

April 16, 2013
(HealthDay)—A fasting plasma glucose value of 4.4 mmol/L is the optimal cut point for determining which pregnant Chinese women need a 75-g 2-h oral glucose tolerance test offered at 24 to 28 weeks' gestation, according ...

Recommended for you

Genomic study brings us closer to precision medicine for type 2 diabetes

September 21, 2018
Most patients diagnosed with type 2 diabetes are treated with a "one-size-fits-all" protocol that is not tailored to each person's physiology and may leave many cases inadequately managed. A new study by scientists at the ...

High gluten diet in pregnancy linked to increased risk of diabetes in children

September 19, 2018
A high gluten intake by mothers during pregnancy is associated with an increased risk of their child developing type 1 diabetes, suggests a study published by The BMJ today.

Anti-inflammatory protein promotes healthy gut bacteria to curb obesity

September 19, 2018
Scientists from the UNC School of Medicine discovered that the anti-inflammatory protein NLRP12 normally helps protect mice against obesity and insulin resistance when they are fed a high-fat diet. The researchers also reported ...

Study reveals the current rates of diagnosed type 1 and type 2 diabetes in American adults

September 18, 2018
A new study from the University of Iowa finds that type 2 diabetes remains overwhelmingly the most common type of diabetes diagnosed in American adults who have the disease.

Research reveals link between immunity, diabetes

September 14, 2018
When it comes to diet-induced obesity, your immune system is not always your friend.

BPA exposure in U.S.-approved levels may alter insulin response in non-diabetic adults

September 14, 2018
In a first study of its kind study, researchers have found that a common chemical consumers are exposed to several times a day may be altering insulin release. Results of the study, led by scientists at the University of ...

0 comments

Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.