Obstructive sleep apnea linked to thinning of calvaria, skull base

Obstructive sleep apnea linked to thinning of calvaria, skull base

(HealthDay)—Obstructive sleep apnea (OSA) is associated with thinning of the calvaria and skull base, according to a study published online May 3 in JAMA Otolaryngology-Head & Neck Surgery.

Cyrus Rabbani, M.D., from Indiana University School of Medicine in Indianapolis, and colleagues conducted a of 1,012 patients who underwent a polysomnogram and had high-resolution computed tomographic imaging of the head. Patients with and without OSA (56 and 58 patients, respectively) were matched for age and .

The researchers found that patients with OSA had thinner mean calvaria (2.73 versus 2.47 mm; difference, −0.26 mm [95 percent confidence interval, −0.49 to −0.04]) and thinner skull bases (5.03 versus 4.32 mm; difference, −0.71 mm [95 percent confidence interval, −1.23 to −0.19]). The mean extracranial zygoma thickness was the same for those with and without OSA (4.92 versus 4.84 mm; difference, −0.07 mm; 95 percent confidence interval, −0.39 to 0.24). In nearly twice as many with versus without OSA, the tegmen mastoideum was dehiscent (37 versus 20 percent; difference, 17 percent; 95 percent interval, 0.4 to 32).

"OSA was independently associated with intracranial bone (calvaria and skull base) thinning and not with extracranial (zygoma) thinning," the authors write. "These findings support a possible role of OSA in the pathophysiologic development of spontaneous cerebrospinal fluid leaks."


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Citation: Obstructive sleep apnea linked to thinning of calvaria, skull base (2018, May 4) retrieved 19 July 2019 from https://medicalxpress.com/news/2018-05-obstructive-apnea-linked-thinning-calvaria.html
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