Weight loss surgery may affect the risk of cancer

A new analysis published in the British Journal of Surgery indicates that weight loss surgery may affect an individual's risk of developing cancer.

This national population-based cohort study used data from the Hospital Episode Statistics database in England collected between 1997 and 2012. A total of 8794 obese patients who underwent , , or sleeve gastrectomy were matched with 8794 obese individuals who did not have surgery.

Patients who underwent surgery had a 77 percent decreased risk of developing hormone-related cancer (breast, endometrial or prostate cancer) when compared with patients who did not have surgery.

Gastric bypass resulted in the largest risk reduction (84 percent) for hormone-related cancer but was associated with a greater than twofold increased risk of colorectal cancer.

Additional studies are needed to understand the biological mechanisms behind these findings.


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More information: H. Mackenzie et al. Obesity surgery and risk of cancer, British Journal of Surgery (2018). DOI: 10.1002/bjs.10914
Journal information: British Journal of Surgery

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Citation: Weight loss surgery may affect the risk of cancer (2018, July 16) retrieved 24 August 2019 from https://medicalxpress.com/news/2018-07-weight-loss-surgery-affect-cancer.html
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