Ultrasound ovarian cancer screening improves survival

ovarian cancer
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A University of Kentucky study just published in Obstetrics & Gynecology shows that annual ultrasound screening of at-risk asymptomatic women increases the survival rates of women with type I and type II epithelial ovarian cancer.

The results come from the UK Markey Cancer Center's Ovarian Cancer Screening Program, a 30-year study initiated in 1987 by gynecologic oncologist Dr. John van Nagell, Jr. and the UK College of Medicine. The goal was to study whether transvaginal sonography (TVS) screening could be an effective means of detection. Women who enrolled in the study were provided a free annual transvaginal ultrasound screening.

To date, more than 46,000 women have been given free screenings. To be eligible, women had to be asymptomatic and either age 50 or older, or age 25 or older with a documented family history of ovarian in a close relative.

Through the study, 71 invasive epithelial ovarian cancers and 17 epithelial ovarian tumors of low malignant potential were found. The 5-, 10-, and 20-year disease-specific survival of patients whose invasive ovarian cancers were detected by screening was more than 30 percent higher than unscreened women with clinically detected ovarian cancer from the same geographic area treated at the Markey Cancer Center.

Credit: University of Kentucky

For the past 50 years, ovarian cancer has remained the leading cause of gynecologic cancer mortality in the United States. This year, more than 14,000 deaths from ovarian cancer will be reported in the United States, making it the fifth leading cause of female cancer mortality. When it is detected early, women often can be cured with existing treatment methods. However, most have no symptoms until the disease has progressed to an advanced stage. As the disease progresses, drop sharply.

"While regular pelvic examination is important and can detect many other abnormalities, including cervical cancer, it is not effective in detecting ovarian cancer in its earliest and most treatable stages," van Nagell said. "This study documents that TVS is safe and is associated with the earlier detection of ."


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More information: John R. van Nagell et al. Survival of Women With Type I and II Epithelial Ovarian Cancer Detected by Ultrasound Screening, Obstetrics & Gynecology (2018). DOI: 10.1097/AOG.0000000000002921
Journal information: Obstetrics & Gynecology

Citation: Ultrasound ovarian cancer screening improves survival (2018, November 1) retrieved 23 October 2019 from https://medicalxpress.com/news/2018-11-ultrasound-ovarian-cancer-screening-survival.html
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