Risk of hospital-treated infections and use of antibiotics after hip fracture surgery

December 5, 2018, Wiley

In a Journal of Bone and Mineral Research study that examined trends in the incidence of infections following hip fracture surgery in Denmark, the risk of postoperative infections (at 15, 30, 90, and 365 days) increased between 2005 and 2016.

The incidence of all hospital-treated infections within 30 days after hip fracture surgery increased by 32 percent, from 10.8 percent in 2005-2006 to 14.3 percent in 2015-2016. The risk of hospital-treated pneumonia within 30 days increased by 70 percent in 2015-2016 compared with 2005-2006. Community-based within 30 days after surgery increased by 54 percent, from 17.5 percent in 2005-2006 to 27.1 percent in 2015-2016.

The study—which included a total of 74,771 aged 65 years or older with first time hip fracture surgery—revealed that risk of infections was substantially higher in hip fracture patients than in the age- and gender-matched general population, and the risk of hospital-treated pneumonia and antibiotic prescriptions increased more over time among hip fracture patients.

"This nationwide study found increasing risk of hospital-treated infections and community-based antibiotic prescriptions after hip fracture surgery during the 12-year study period, which could not entirely be explained by increases seen in the ," said lead author Kaja Kjørholt, of Aarhus University Hospital, in Denmark. "Given the high mortality following infections in elderly individuals, future research and clinical work should focus on improving our understanding of the risk factors and patient profiles associated with postoperative infections. Knowledge of risk factors may enable cost-effective preventive measures and treatment protocols to reduce infections and mortality."

Explore further: Many diseases increase the risks of hip fracture surgery

More information: Kaja E Kjørholt et al, Increasing Risk of Hospital-Treated Infections and Community-Based Antibiotic Use After Hip Fracture Surgery: A Nationwide Study 2005-2016, Journal of Bone and Mineral Research (2018). DOI: 10.1002/jbmr.3620

Related Stories

Many diseases increase the risks of hip fracture surgery

November 30, 2018
Parkinson's disease, osteoarthritis, rheumatic diseases, alcoholism and mental health disorders increase the risk of surgical complications after a hip fracture surgery, a new Finnish study analysing nationwide registers ...

Lower post-op mortality with hip fx surgery on day of admission

August 24, 2018
(HealthDay)—Postoperative mortality is lower for medically stable older patients who undergo surgery for hip fracture on the day of admission or the following day, according to a study published in the Aug. 7 issue of CMAJ, ...

Increased risk of MI, stroke for patients with hip fracture

August 24, 2017
(HealthDay)—Patients with hip fracture have an increased risk of myocardial infarction (MI) and stroke, according to a study published online Aug. 21 in the Journal of Bone and Mineral Research.

Cataracts linked to higher risks of osteoporosis and fracture

October 3, 2018
A new Journal of the American Geriatrics Society study has evaluated the potential impacts of cataracts and cataract surgery on the risks of osteoporosis and bone fractures.

Factors for higher risk of death following hip fracture surgery than hip replacement

September 15, 2015
Patients undergoing surgery for a hip fracture were older and had more medical conditions than patients who underwent an elective total hip replacement, factors that may contribute to the higher risk of in-hospital death ...

The sun should not set twice before hip fracture repair

August 7, 2018
Optimal timing to reduce mortality after hip surgery in medically stable older patients is on the day of admission or the following day, according to a large study published in CMAJ (Canadian Medical Association Journal).

Recommended for you

Surgical adhesions can be treated, prevented in mice

November 28, 2018
A cellular culprit—as well as a possible treatment—for a common, sometimes life-threating post-surgical complication has been identified by researchers at the Stanford University School of Medicine.

Cost and weight-loss potential matter most to bariatric surgery patients

November 28, 2018
A JAMA Surgery study found that patients are likely to base their weight loss surgery choice on expected out-of-pocket costs, and how much weight they can lose—not risk of complications or recovery time.

Treating spinal pain with replacement discs made of 'engineered living tissue' moves closer to reality

November 21, 2018
For the first time, bioengineered spinal discs were successfully implanted and provided long-term function in the largest animal model ever evaluated for tissue-engineered disc replacement. A new Penn Medicine study published ...

Screening for colorectal cancer spares male patients from intense treatments

November 21, 2018
While screening for colorectal cancer does not reduce mortality, it does reduce the need for chemotherapy and emergency surgeries among male patients, according to a recent Finnish study.

Rapid response inpatient education boosts use of needed blood-thinning drugs

November 16, 2018
A new study designed to reach hospitalized patients at risk shows that a "real-time" educational conversation, video or leaflet can lower the missed dose rates of drugs that can prevent potentially lethal blood clots in their ...

Race plays role in regaining weight after gastric bypass surgery

November 15, 2018
African Americans and Hispanic Americans who have undergone Roux-en-Y gastric bypass (RYGB) are at greater risk to regain weight as compared to Caucasians. To date, no study has addressed the effect of race on weight regain ...


Please sign in to add a comment. Registration is free, and takes less than a minute. Read more

Click here to reset your password.
Sign in to get notified via email when new comments are made.