Statins linked to higher diabetes risk

Individuals who take cholesterol-lowering statins may be at higher risk for developing high blood sugar levels, insulin resistance, and eventually type 2 diabetes, according to an analysis published in the British Journal of Clinical Pharmacology.

The analysis examined information from 9,535 individuals older than 45 years of age who were free from diabetes at the start of the population-based Rotterdam Study and were followed up to 15 years.

Compared with participants who never used statins, those who used statins tended to have higher concentrations of serum fasting insulin and . Participants who ever used statins had a 38 percent higher risk of developing type 2 diabetes during the study. This risk was more prominent in individuals with impaired glucose balance and in overweight/.

"The findings suggest that in patients who initiate statin therapy, preventive strategies such as blood sugar control and may be warranted for minimizing the risk of diabetes," said senior author Prof. Bruno Stricker, of the Erasmus Medical Centre, in the Netherlands.


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More information: Fariba Ahmadizar et al, Associations of statin use with glycaemic traits and incident type 2 diabetes, British Journal of Clinical Pharmacology (2019). DOI: 10.1111/bcp.13898
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Citation: Statins linked to higher diabetes risk (2019, March 6) retrieved 13 November 2019 from https://medicalxpress.com/news/2019-03-statins-linked-higher-diabetes.html
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