Statins linked to lower risk of early death in patients with colorectal cancer

Colorectal cancer
Cancer — Histopathologic image of colonic carcinoid. Credit: Wikipedia/CC BY-SA 3.0

Use of statins before or after a diagnosis of colorectal cancer was linked with a lower risk of premature death, both from cancer and from other causes, in a Cancer Medicine analysis of published studies.

The meta-analysis included 14 studies involving 130,994 patients with colorectal . Pre-diagnosis statin use was linked with a 15 percent lower risk of dying early from any cause and an 18 percent lower risk of dying from cancer. Post-diagnosis statin use was linked with a 14 percent lower risk of all-cause death and a 21 percent lower risk of cancer-specific death.

"Considering that statins are low-costed and wildly-used worldwide, we believe our updated meta-analysis can provide new insights into optimizing adjuvant treatment of ," the authors wrote.


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More information: Yue Li et al, Statin uses and mortality in colorectal cancer patients: An updated systematic review and meta‐analysis, Cancer Medicine (2019). DOI: 10.1002/cam4.2151
Journal information: Cancer Medicine

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Citation: Statins linked to lower risk of early death in patients with colorectal cancer (2019, May 9) retrieved 18 August 2019 from https://medicalxpress.com/news/2019-05-statins-linked-early-death-patients.html
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