COVID-19 vaccine effectively cuts infection in pregnant women

COVID-19 vaccine effectively cuts infection in pregnant women

(HealthDay)—The Pfizer-BioNTech COVID-19 vaccine is associated with a significantly lower risk for severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) infection in pregnant women, according to a study published online July 12 in the Journal of the American Medical Association.

Inbal Goldshtein, Ph.D., from Maccabi Healthcare Services in Tel Aviv, Israel, and colleagues used data from a pregnancy registry (including 7,530 vaccinated and 7,530 matched unvaccinated women) to assess the association between receipt of the BNT162b2 mRNA vaccine and the risk for SARS-CoV-2 infection among pregnant women.

The researchers noted 118 SARS-CoV-2 infections in the vaccinated group and 202 in the unvaccinated group. In the vaccinated group, 83.8 percent were symptomatic versus 83.2 percent in the unvaccinated group (P ≥ 0.99). However, in the 28 to 70 days of follow-up, there were 10 infections in the vaccinated group and 46 in the unvaccinated group, yielding hazards of infection of 0.33 and 1.64 percent, respectively (absolute difference: 1.31 percent; adjusted hazard ratio, 0.22). Sixty-eight patients reported vaccine-related adverse events, including headache (0.1 percent), general weakness (0.1 percent), nonspecified pain (<0.1 percent), and stomachache (<0.1 percent); no severe reactions were reported.

"In this retrospective cohort study of , BNT162b2 mRNA vaccination compared with no vaccination was associated with a significantly of SARS-CoV-2 infection," the authors write. "Interpretation of study findings is limited by the observational design."


Explore further

Two doses of BNT162b2 SARS-CoV-2 vaccine highly effective

More information: Abstract/Full Text

Copyright © 2021 HealthDay. All rights reserved.

Citation: COVID-19 vaccine effectively cuts infection in pregnant women (2021, July 21) retrieved 29 July 2021 from https://medicalxpress.com/news/2021-07-covid-vaccine-effectively-infection-pregnant.html
This document is subject to copyright. Apart from any fair dealing for the purpose of private study or research, no part may be reproduced without the written permission. The content is provided for information purposes only.
3 shares

Feedback to editors

User comments